Neiella holothuriorum sp. nov., isolated from the gut of a sea cucumber Apostichopus japonicus.

A Gram-stain negative, aerobic, rod-shaped bacterium, designated 126, was isolated from the intestinal content of a sea cucumber, Apostichopus japonicus, in China. Strain 126 was found to grow optimally at 25-28 °C and pH 7.5-8.

[The study of the secondary metabolites from fungus Paecilomyces sp].

Objective: To get active secondary metabolites from the fungus Paecilomyces sp..

Methods: The strain Paecilomyces sp.

[Study on the second metabolisms from fungus HS-1 Epicoccum spp. from the sea cucumber in Yellow Sea].

Objective: To get active metabolites from the microbes associated with sea cucumber.

Methods: Fungus was isolated from the sea cucumber, and the species was identified by molecular biology, and then was cultivated in GYP medium, and the metabolites were got by chromatography. Their structures were identified by comprehensive spectroscopic methods.

[The secondary metabolites of the mangrove endophytic fungi ZZF13 and Guignardia sp. 4382 from the South China Sea].

Objective: The secondary metabolites of the fungus ZZF13 isolated from the leaves of the mangrove sample Kandelia candel in Zhanjiang and Guignardia sp. 4382 isolated from bark of Kandelia candel (endophyte) of Mai Po, Hong Kong were studied.

Methods: The compounds were isolated by siliga gel, and their structures were identified by IR, MS and NMR.

Antioxidant activity of chito-oligosaccharides on pancreatic islet cells in streptozotocin-induced diabetes in rats.

Aim: To investigate the antioxidant activity of chito-oligosaccharides (COSs) on pancreatic islet cells in diabetic rats induced by streptozotocin.

Methods: The antioxidant effect of COSs on pancreatic islet cells was detected under optical microscopy and with colorimetric assay and gel electrophoresis. The activities of glutathione peroxidase and superoxide dismutase, total antioxidant capacity, and content of malondialdehyde in serum and tissue slices of pancreas were examined after 60 d to determine the effect of COSs in streptozotocin-induced diabetes in rats.