Publications by authors named "Mian Zi Tee"
Article Synopsis
- Skin infections significantly burden underserved communities, particularly the isolated Negrito tribes of Peninsular Malaysia, with a notable study revealing a 35.6% overall prevalence.
- Major infections found were scabies (11.7%), tinea versicolor (11.3%), and tinea imbricata (7.5%), with higher rates in resettled villages compared to inland ones.
- The study emphasizes the need for targeted interventions, linking specific infections to environmental factors and lifestyle choices, to improve healthcare access and support for these communities.
Article Synopsis
- Indigenous populations, like certain Malaysian villages, show microbiomes that are diverse and less understood compared to those in industrialized societies, particularly regarding helminth (worm) infections.
- Villages with higher helminth infection rates exhibited more unmapped genetic data and greater microbial diversity, with differences in microbiome composition related to specific localities and associated infection status.
- Treatment with albendazole (a deworming drug) caused changes in both infected and uninfected individuals' microbiomes, highlighting the complex interactions between helminths and microbiota, and emphasizing the need for careful interpretation in deworming research.
Soil-transmitted intestinal worms known as helminths colonize over 1.5 billion people worldwide. Although helminth colonization has been associated with altered composition of the gut microbiota, such as increases in Clostridia, individual species have not been isolated and characterized.
View Article and Find Full Text PDFIn Malaysia, soil-transmitted helminth (STH) infections still persist among indigenous communities. In the past, local studies have focused mostly on epidemiologic aspects of STH infections with a scarcity of information on the efficacy of deworming treatment. The present study consisted of 2 phases: a cross-sectional phase on current epidemiological status and risk factors of STH infections and a longitudinal study over 6 weeks on triple dose albendazole efficacy against STH infections.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the prevalence of intestinal parasitic infections (IPIs) in two indigenous sub-ethnic groups in Malaysia (Temuan and Mah Meri), highlighting that previous research often overlooked polyparasitism and the diversity of cultural practices among different groups.
- Conducted as a cross-sectional study, it involved collecting and analyzing faecal samples from 186 participants to identify infections and assessing risk factors through questionnaires regarding demographics and behaviors.
- Results showed that trichuriasis was the most common infection in both groups, with the Temuan community presenting a prevalence of 64.2%, while Mah Meri had an even higher rate of 77.5%, indicating significant variations in infection rates between the two sub-eth