Improvement of bowel dysfunction with sacral neuromodulation for refractory urge urinary incontinence.

Introduction And Hypothesis: Sacral nerve stimulation (SNS) is approved for urologic indications in the USA and, recently, fecal incontinence. This study described concomitant bowel dysfunction and improvements in bowel and urinary symptoms and quality of life (QOL) in women with refractory urge urinary incontinence (UUI) receiving SNS.

Methods: Women (N = 36) with refractory UUI receiving SNS were prospectively enrolled.

Improved sexual and urinary function in women with sacral nerve stimulation.

Objectives:   Urinary and sexual function improve following sacral nerve stimulation (SNS) for refractory overactive bladder. No significant associations between these changes have been found. Whether improvements in sexual function are independent of or secondary to improvements in urinary function remains unclear.

Perioperative management of patients undergoing sling surgery: a survey of US urologists.

Objectives: Anti-incontinence procedures are common. However, perioperative practices are variable and no consensus guidelines exist. Our primary objective was to describe contemporary management of patients undergoing routine sling surgery alone.

Risk of infection after midurethral synthetic sling surgery: are postoperative antibiotics necessary?

Objectives: To review our postoperative infections using single-dose preoperative antibiotics. Midurethral synthetic sling surgery is commonly performed. Postoperative antibiotics are often prescribed and may have some risk of adverse events (AEs).

Patient perceived effectiveness of a new male sling as treatment for post-prostatectomy incontinence.

Purpose: Objective measures show the AdVance() sling provides some benefit in post-prostatectomy incontinence. To our knowledge no validated, patient determined outcomes have been used to assess this procedure. We described the patient perceived effectiveness and postoperative complications.

Single-port laparoscopic abdominal sacral colpopexy: initial experience and comparative outcomes.

Objectives: To determine the efficacy and safety of single-port laparoscopic abdominal sacral colpopexy (ASC) for the treatment of female pelvic organ prolapse (POP).

Methods: A retrospective cohort study was performed to assess perioperative outcomes among women who were treated for symptomatic POP with laparoscopic, robotic, or single-port laparoscopic ASC. All patients underwent preoperative history and physical examination including POP quantification (POP-Q) staging and urodynamics.

Complications of mid urethral slings: important outcomes for future clinical trials.

Purpose: Mid urethral slings are becoming the first line surgical treatment for stress urinary incontinence in women. We reviewed the complications of mid urethral sling placement and their potential pathophysiology.

Materials And Methods: We conducted a literature search on MEDLINE from 1995 to 2007 using the key words sling, complications, mid-urethral slings, transvaginal tape, transobturator tape, trials, pathophysiology and complications.

Admission for nephrolithiasis in pregnancy and risk of adverse birth outcomes.

Objective: Nephrolithiasis occurring during pregnancy may be associated with an elevated risk of preterm delivery and other adverse birth outcomes. The goal of this study was to describe the association between these outcomes and admission for nephrolithiasis during pregnancy.

Methods: We performed a retrospective cohort study using birth certificate records linked to Washington State hospital discharge data from 1987-2003 to compare pregnant women admitted for nephrolithiasis and randomly selected pregnant women without nephrolithiasis.

Complications of scrotal surgery for benign conditions.

Objectives: Frequent complications have been reported after scrotal surgery. We reviewed our experience to determine the complication rates, risk factors, and how our experience might differ from other series.

Methods: We reviewed all scrotal surgery for benign conditions at the Veterans Affairs Puget Sound Health Care System from 1998 to 2004.

Incidence of primary urethral carcinoma in the United States.

Objectives: Primary urethral carcinoma is rare, and the demographic correlates of its incidence have not been examined using population-based data.

Methods: The National Cancer Institute Surveillance, Epidemiology, and End Results database was used to identify persons diagnosed with primary urethral carcinoma from 1973 to 2002. During this period, the Surveillance, Epidemiology, and End Results program included population-based tumor registries in nine geographic areas that represented approximately 10% of the U.

Modified bladder neck reconstruction in patients with incontinence after staged exstrophy/epispadias closures.

Purpose: Reconstruction of the urethra without adequate circumferential muscular support is a significant problem in bladder neck surgery for urinary incontinence. Fascial, muscular and artificial slings have been used for support of the bladder neck after reconstruction. We used a demucosalized detrusor muscle pedicle to wrap around the bladder neck base along with other continence techniques in children who experienced incontinence after staged closure of exstrophy and epispadias.

Renal medullary carcinoma: clinical, pathologic, immunohistochemical, and genetic analysis with pathogenetic implications.

Objectives: To investigate the pathologic, clinical, and genetic features of renal medullary carcinomas (RMCs) in search of clues to their pathogenesis.

Methods: We analyzed 40 RMCs for clinical features, for immunohistochemical expression using a panel of markers, and for genetic changes using comparative genomic hybridization.

Results: Patients presented at 5 to 32 years of age, and 82% were African American.