Publications by authors named "Mia E Michel"
Article Synopsis
- - The electrical synapse density (ESD) is a macromolecular complex involving neuronal gap junction channels, crucial for regulating electrical transmission and network function, but its protein makeup is not fully understood.
- - In zebrafish, the protein ZO1b, a component of the ESD, exists in three isoforms—ZO1b-Alpha, -Beta, and -Gamma—each with distinct functions and expression patterns, where Beta is essential for gap junction channel localization.
- - This research highlights the complexity of ESD by showing that distinct isoforms from a single gene can differentially contribute to the formation and function of electrical synapses, affecting overall neural development and behavior.
