Publications by authors named "Mi-mi Xu"
Article Synopsis
- Allergic rhinitis (AR) is a common allergic condition caused by various allergens, and the study investigates how Guanylate-binding protein 2 (GBP2) affects AR.
- Researchers created an AR model in mice using ovalbumin (OVA) and found that elevated levels of IgE, IgG1, inflammation markers, and abnormal lipid profiles were present in these mice.
- The study showed that GBP2 could reduce inflammation, oxidative stress, and lipid metabolism changes by inhibiting the HIF-1 pathway, suggesting a potential treatment approach for AR.
[The Role and Mechanism of Tfh and B Cell in Human Chronic Graft-Versus-Host-Disease].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2022
Article Synopsis
- The study aimed to explore the role of different immune cell types, specifically circulating follicular helper T cells (cTfh), extrafollicular helper T cells, and B cells, in chronic graft-versus-host disease (cGVHD) following stem cell transplantation.
- It was found that patients with cGVHD had significantly decreased levels of cTfh cells and increased levels of extrafollicular helper T cells compared to healthy donors, indicating a shift in immune response.
- Additionally, there were notable changes in B cell subsets, with higher percentages of antigen-stimulated B cells and a reduction in naive B cells, suggesting an altered immune landscape in cGVHD patients.
[Treatment of Persistent Somatoform Pain Disorder by Floating Needle Therapy and Duloxetine].
Zhongguo Zhong Xi Yi Jie He Za Zhi
February 2016
Objective: To evaluate clinical effect and safety of floating needle therapy and duloxetine in treating patients with persistent somatoform pain disorder (PSPD).
Methods: Totally 108 PSPD patients were randomly assigned to the floating needle treatment group, the duloxetine treatment group, and the placebo treatment group, 36 in each group. Patients in the floating needle treatment group received floating needle therapy and placebo.
Conclusion: Nasal polyposis (NP) is frequently found to run in families. Earlier onset of the condition strongly suggested the genetic basis for the development of NP and implied that it might be a genetic disease involving multiple genes.
Objective: The etiology and pathogenesis of NP remain largely unknown, although it is assumed to be associated with allergic reaction and infection.
Background: This study evaluates the feasibility of endoscope-assisted second branchial cleft cyst resection via retroauricular approach by comparing it with conventional cervical incision for removal of second branchial cleft cyst.
Methods: From January 2009 to December 2010, 25 patients were randomly assigned to the endoscope-assisted surgery group (13 patients) or the conventional surgery group (12 patients). The clinical characteristics of patients, operation time, operative bleeding volume, postoperative complications, and subjective satisfaction with incision scar checked by visual analog scale were compared between the groups, retrospectively.