Risk factors of hypotension during cesarean section with spinal anesthesia in parturients with COVID-19: a retrospective study in comparison with pregnant women without COVID-19.

Background: The incidence of hypotension in parturients with coronavirus disease (COVID-19) undergoing regional anesthesia remains controversial. This study aimed to investigate the incidence of hypotension during spinal anesthesia in parturients infected with COVID-19, as well as to identify associated risk factors.

Methods: This retrospective study compared COVID-19-positive parturients who underwent cesarean section under spinal anesthesia (COVID-19 group) with a control group between January 2017 and June 2022.

Accuracy of customized abutment data superimposition according to the extent of scanning area.

Purpose: To evaluate the accuracy of superimposition of customized abutment library data onto scanned abutment data according to the extent of the scanning area.

Materials And Methods: A patient model was fabricated by a 3D printer (Probo, DIO Implant), and a customized abutment was fabricated using a four-axis milling machine (ARUM 4X-100, Doowon). The customized abutment library data were generated using a laboratory scanner (E3, 3Shape) for superimposition after intraoral scanning.

Fracture Strength After Fatigue Loading of Lithium Disilicate Pressed Zirconia Crowns.

Purpose: The aim of this study was to evaluate the fracture resistance of fatigued lithium disilicate pressed zirconia crowns versus other ceramic crowns.

Materials And Methods: Lithium disilicate pressed zirconia, fluorapatite pressed zirconia, monolithic lithium disilicate, and monolithic zirconia crowns were fabricated. Cyclic and static loadings were applied to the mesiobuccal cusp tip after thermocycling and fracture strengths were recorded.

Marginal and Internal Fit of Conventional Metal-Ceramic and Lithium Disilicate CAD/CAM Crowns.

This study aimed to evaluate and compare the marginal and internal gap widths of lithium disilicate computer-aided design / computer-assisted manufacture (LDC) crowns and conventionally produced porcelain-fused-to-metal (PFM) crowns. A convenience sample of 21 patients treated with a single restoration was selected. PFM and LDC crowns were fabricated for each selected abutment tooth, following traditional crown preparation.

Implant overdenture using a locator bar system by drill and tapping technique in a mandible edentulous patient: a case report.

Various options have been introduced for the selection of implant overdenture attachments. Attachment wear due to the repeated insertion and removal of dentures has caused problems such as decreased retention and the requirement for suprastructure remanufacturing. In these cases, a Locator bar system was applied using the drill and tapping technique to achieve total retrievability.

Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4.

Paecilomyces cicadae have been reported to have immunomodulatory properties. In this study, we investigated the effect of polysaccharide (PCP) isolated from P. cicadae on the macrophages.

Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma.

The presence of active immunity within the brain supports the possibility of effective immunotherapy for glioblastoma (GBM). To provide a clinically-relevant adoptive immunotherapy for GBM using ex vivo expanded cytokine-induced killer (CIK) cells, the treatment capability of CIK cells, either alone or in combination with temozolomide (TMZ) were evaluated. Human CIK (hCIK) cells were cultured from PBMC using activating anti-CD3 antibody and IL-2, which were 99% CD3+, 91% CD3+CD8+ and 29% CD3+CD56+.

Extracellular ATP is involved in the induction of apoptosis in murine hematopoietic cells.

Extracellular nucleotides have multiple biological actions in processes such as proliferation, differentiation, chemotaxis, and cytokine secretion through P2X receptors on the cell surface. To determine the biological activity of adenosine triphosphate (ATP) and the expression of P2 nucleotide receptors in murine bone marrow-derived hematopoietic cells and stem cells/progenitor cells, we investigated the effects of ATP in assays of cell proliferation and cell death in vitro. Our results demonstrated that several subtypes of P2X receptors were expressed on hematopoietic cells and that P2X7, in particular, was partially expressed in hematopoietic stem cells/progenitor cells.

Extracellular ATP induces apoptotic signaling in human monocyte leukemic cells, HL-60 and F-36P.

Extracellular adenosine 5'-triphosphate (ATP) affects the function of many tissues and cells. To confirm the biological activity of ATP on human myeloid leukemic cells, F-36P and HL-60, cells were treated with a variety of concentrations of ATP. The stimulation with extracellular ATP induced the arrest of cell proliferation and cell death from the analysis of Annexin-V staining and caspase activity by flow cytometry.