Publications by authors named "Mi Zhu Sun"
Article Synopsis
- Alcohol abuse leads to tissue and organ damage and may contribute to neuropsychiatric disorders, with DNA methylation influencing gene expression and behavior changes.
- A study with 32 male SD rats examined the effects of chronic alcohol exposure on DNA methylation in the medial prefrontal cortex (mPFC) using various tests and sequencing techniques.
- Results showed that chronic alcohol significantly increased methylation levels in the mPFC, which correlated with altered mRNA expression of several genes and elevated levels of DNA methyltransferases (DNMT3B) and MeCP2, suggesting a link between DNA methylation and alcohol abuse development.
