Publications by authors named "MhmtJamil L Alkhalaf"
Article Synopsis
- Transcutaneous cervical vagus nerve stimulation (tcVNS) is explored as a treatment for stress-related psychiatric disorders, with ghrelin identified as a possible stress biomarker.
- A randomized double-blind study found that tcVNS lowers ghrelin levels significantly during and after stress-inducing tasks compared to a sham treatment.
- The study suggests that tcVNS helps regulate hormonal responses to stress, although there are limitations such as measurement timing and the stimulation focused only on the left vagus nerve.
Transcutaneous Cervical Vagal Nerve Stimulation in Patients with Posttraumatic Stress Disorder (PTSD): A Pilot Study of Effects on PTSD Symptoms and Interleukin-6 Response to Stress.
J Affect Disord Rep
December 2021
Background: Posttraumatic stress disorder (PTSD) is a highly disabling condition associated with alterations in multiple neurobiological systems, including increases in inflammatory and sympathetic function, responsible for maintenance of symptoms. Treatment options including medications and psychotherapies have limitations. We previously showed that transcutaneous Vagus Nerve Stimulation (tcVNS) blocks inflammatory (interleukin (IL)-6) responses to stress in PTSD.
View Article and Find Full Text PDFTranscutaneous vagal nerve stimulation blocks stress-induced activation of Interleukin-6 and interferon-γ in posttraumatic stress disorder: A double-blind, randomized, sham-controlled trial.
Brain Behav Immun Health
December 2020
Posttraumatic stress disorder (PTSD) is a highly disabling condition associated with alterations in multiple neurobiological systems, including increases in inflammatory function. Vagus nerve stimulation (VNS) decreases inflammation, however few studies have examined the effects of non-invasive VNS on physiology in human subjects, and no studies in patients with PTSD. The purpose of this study was to assess the effects of transcutaneous cervical VNS (tcVNS) on inflammatory responses to stress.
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