Publications by authors named "Mezza G"

Article Synopsis
  • Matrix metalloproteinases (MMPs) are key players in tumor growth and spread, and the compound 4'-geranyloxyferulic acid (GOFA) shows promise for its anti-tumor and anti-inflammatory effects.
  • In experiments with U937 and HCT116 cancer cells, GOFA was found to reduce abnormal cell growth and MMP-9 activity caused by lipopolysaccharide (LPS), leading to decreased cell migration.
  • The study suggests that GOFA's ability to inhibit the ROS/ERK pathway and prevent apoptosis and senescence may make it a valuable therapeutic option to combat tumor metastasis.
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The objective of this study was to evaluate the antioxidant activity of rosemary essential oil fractions obtained by molecular distillation (MD) and investigate their effect on the oxidative stability of sunflower oil. MD fractions were prepared in a series of low-pressure stages where rosemary essential oil was the first feed. Subsequently, a distillate (D1) and residue (R1) were obtained and the residue fraction from the previous stage used as the feed for the next.

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Actinomycosis of the female genital tract has greatly increased over the last two decades. A pelvic form of the disease, associated with the use of Intra-uterine Devices (IUD), can severely damage pelvic organs and even can lead to death. We report a case of pelvic actinomycosis presenting as cutaneous fistula.

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In the rat, narcotic doses of Althesin injected intraperitoneally did not modify blood glucose concentration nor plasma insulin concentration. On the contrary a reduction of blood glucose concentration, associated with an increase of plasma insulin concentration was observed when narcotic doses of thiopental and ketamine were. Plasma renin concentration decreased after injection of Althesin and thiopental while increased after injection of ketamine.

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The Authors, thanks to experimental works, have established that piribedil at high concentrations inhibits ADP and thrombin aggregation effect on the rabbit PRP.

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Experimental research has shown that pirenzepina possesses interesting inhibiting properties with respect to gastric secretion and the formation of experimentally induced gastric ulcers.

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An experimental comparative study has been undertaken to evaluate the action of salmefamol and salbutamol, two sympathomimetic drugs specific for the beta-receptors, on tracheal and bronchial smooth muscles. Salmefamol showed a more intense, longer-lasting beta-adrenergic activity than salbutamol did.

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