[Thyroid status in anemic pregnant women under conditions of endemic goiter].

Anemia is a highly prevalent condition among pregnant women in the Republic of Kazakhstan. The causes of this anemia are not quite clear, as is the problem of resistance of this type of anemia to therapy with iron preparations. The authors propose that this may be explained by the fact that many regions of the Republic are foci of endemic goiter, because tentative studies indicate a relationship between endemic goiter and hypothyrosis.

[Features of adaptation of newborns born to mothers with endemic goiter].

Relationships between chronic iodine deficiency and, among other things, endemic goiter in women and adaptation of their babies in the early neonatal period were studied. A total of 125 women with endemic goiter of the Ist-IInd degrees and their newborns were examined. The diagnosis of endemic goiter was verified by the findings of an objective examination, ultrasonic examination, and puncture biopsy of the thyroid.

[Endometrial Chlamydia infection in women with habitual abortion].

Endometrial, endocervical, and urethral specimens were obtained from 16 nonpregnant women with a history of habitual abortions. Chlamydia were isolated from the endometria of 4 women, but only in one case chlamydial intracytoplasmic incorporations in endometrial cells were detectable by the Romanovsky Giemza staining. Endometrial Chlamydia infection was diagnosed in 5 of the 16 patients.

[Effect of anti-chlamydial drugs on the effectiveness of the treatment of habitual abortion].

An examination of 163 females suffering from habitual miscarriage revealed chlamydia in 41.7%. The miscarriage rate was 59.

[Effect of early initiation of breast feeding and the individualized feeding system on lactation].

Examination of 109 mothers included a radioimmune assay for prolactin. Higher prolactin levels in blood, greater milk output and better composition of milk composition correlated with early initiation of breastfeeding. Postnatal restoration of birth weight was more rapid in their newborns.

[Urogenital chlamydia infection in women with habitual abortion].

The Chlamydozoan population was identified in 43.6 per cent of 110 females with a history of habitual abortion. It was found that the infection was more frequent in females aged under 30 years, in those who was born preterm, in patients with early (premarital) sexual contacts or those with spontaneously stopped pregnancy during the first trimester, as well as in those females who suffered from cervicitis, yeast colpitis, pyelonephritis or had post-inflammatory changes of placental tissue.

[Risk factors for the development of endometrial cancer in uterine myoma].

It was shown that the risk for endometrial cancer development in uterine myoma increases 43-fold in cases of diabetes mellitus, hypertension and obesity, 20-fold in adnexitis, 15-fold in hyperplastic endometrial lesions and 9.8-fold in the multipara.

[Cellular immunity indices in benign breast tumors].

Patients with breast cancer, localized fibroadenomatosis and healthy females were examined for the initial state of cell immunity: the reaction of delayed hypersensitivity to DNCB, the absolute and relative amount of rosette forming cells (T-lymphocytes) and the stimulation of lymphocytes under exposure to PHA. A considerable suppression of cell immunity was shown both in breast cancer patients and in patients with benign tumors. The indices of skin allergic test and reaction of spontaneous rosette formation were nearly identical in both groups of the patients under examination.

[Use of hormone loading tests for assessing the source of hyperestrogenism and the functional state of the ovaries in breast cancer patients in menopause].

The source of hyperestrogenia was ascertained in 12 patients by dexametasone-infecundin test, and the ovarian hormonal activity in 5 patients by dexametasone-choriogonin test. The source of hyperestrogenia was found to be the adrenal glands in 50%, ovaries--in 30% and the adrenal together with ovaries--in 20%. Ovarian hormonal activity was retained in 3 of 5 patients under examination.

[Hormonal correlations in hyperplasia of the breasts in women with ovulatory cycles].

An excretion of the follicle-stimulating hormone (FSH), estrogens, pregnandiol, 17-KS, vaginal cytology were studied in 22 patients with dyshormonal hyperplasias of mammary glands and in 12 healthy females with ovulatory cycles. The age of patients under study ranged from 20 to 49 years. The patients showed a higher level of excretion of FSH, estriol, pregnandiol and a lower level of 17-KS excretion than healthy persons.