Publications by authors named "Meysam Hasannejad Bibalan"

Objectives: Metabolic syndrome (MetS) is a serious concern among postmenopausal women which predisposes them to cardiovascular and cognitive disorders. Healthful diet and exercise training have been essential strategies to prevent the progress of MetS. The aim of this study was to evaluate the effect of supplementation with a native potential probiotic and high-intensity interval training (HIIT) for 8 weeks on retention of associative memory in rats with ovariectomy- induced metabolic syndrome.

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The present study investigated the antimicrobial and anti-biofilm effects of indigenous Lactobacillus probiotic strains on Pseudomonas aeruginosa isolated from burn wound infection in laboratory conditions. The effect of 7 probiotic strains isolated from infant faeces on the pathogenicity factors of P. aeruginosa, including protease, elastase, antibiofilm and antipyocyanin was measured.

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Objectives: This study aimed to investigate the interactive effect of supplementation with a native potential probiotic lactobacillus and 8-week high-intensity interval training (HIIT) on insulin resistance and dyslipidemia in a menopause-induced metabolic syndrome.

Methods: A total of 40 ovariectomized (OVX) Wistar rats were divided into five groups: control (OVX + Vehicle), exercise (EXE) (OVX + Exe), probiotic (Prob) (OVX + Prob), exercise and probiotic (OVX + Exe + Prob), and sham surgery. After the end of the treatment interventions, body weight, body mass index (BMI), waist circumference (WC), visceral fat, and serum concentrations of glucose, insulin, lipid profile, and adiponectin were measured using colorimetric analysis and enzyme-linked immunosorbent assay, respectively.

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Article Synopsis
  • - The study aimed to isolate specific strains from fecal samples and examine their antimicrobial properties against foodborne pathogens while assessing gene expression related to bacteriocin production.
  • - Fecal samples from healthy individuals were analyzed, showing that the selected strain effectively inhibited four foodborne pathogens and had a strong capacity to adhere to human intestinal cells (Caco-2).
  • - Key bacteriocin-related genes were found to be upregulated when the selected strain was co-cultured with diarrheagenic serotypes, suggesting these strains could potentially be used as alternative antimicrobial agents to combat food contamination and related diseases.
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Article Synopsis
  • * A systematic review was conducted using data from various research databases, resulting in the analysis of seven relevant studies published from 2010 to 2017.
  • * The findings indicate that the overall prevalence of invasive infections among hospitalized Iranian children is low at 2.5%, highlighting the need for more research, particularly in eastern regions.
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Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the global outbreak of coronavirus disease 2019 (Covid-19), which has been considered as a pandemic by WHO. SARS-CoV-2 encodes four major structural proteins, among which spike protein has always been a main target for new vaccine studies. This in silico study aimed to investigate some physicochemical, functional, immunological, and structural features of spike protein using several bioinformatics tools.

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Objective: The present study aimed to investigate the frequency and antibiotic susceptibility pattern of Gram-negative bacteria (GNB) isolated from surgical site infections (SSIs) in the North of Iran.

Results: This cross-sectional study conducted over a two-year period during 2018-2020 on all cases of SSIs who had a positive culture for a GNB. Standard microbiological tests were followed for the bacterial isolation and identification.

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Inflammatory bowel disease (IBD) comprises two major illnesses: Crohn's disease (CD) and ulcerative colitis (UC). Dextran sulfate sodium (DSS) mouse colitis model has been used in understanding the mechanism of IBD. This study was conducted to examine selected Lactobacillus spp.

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Purpose: The pathogenesis of Pseudomonas aeruginosa is multifactorial and attributed to the production of several cell-associated and extracellular virulence factors including those implicated in adherence, iron uptake, exoenzymes (Exo) and exotoxins. The present study aimed to determine the prevalence of type III secretion systems (T3SS) effectors in Iranian burn patients with P. aeruginosa wound infection.

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Background: is the most common causes of hospital-acquired diarrhea affecting particularly hospitalized patients globally. This organism has re-emerged in recent years with significant morbidity and mortality. The present study aimed to estimate the burden of infection (CDI) and to acquire information on the overall rates of community- and hospital-acquired CDI in western Asia.

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Article Synopsis
  • * A study looked at published research between 2000 and 2017 to see how well a drug called tedizolid works against MRSA, finding that most MRSA strains were sensitive to it.
  • * The study showed that while tedizolid works well against MRSA, more research is needed to confirm these findings and help people in real-life situations.
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Objectives: Genetic determinants conferring resistance to macrolide, lincosamide, and streptogramin B (MLS) via ribosomal modification such as, , and genes are distributed in bacteria. The main goals of this work were to evaluate the dissemination of MLS resistance phenotypes and genotypes in methicillin-resistant (MRSA) isolates collected from clinical samples.

Methods: A total of 106 MRSA isolates were studied.

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Wide distrubution of multidrug-resistant Acinetobacter baumannii strains has become a foremost concern in hospital environments. Treatment of infections caused by multidrug resistant strains has conventionally involved the use of β-lactams such as carbapenems. In this study, we report the distribution of carbapenemase genes in A.

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Article Synopsis
  • The study aimed to assess the presence of genes linked to aminoglycoside resistance in the bacteria E. faecalis and E. faecium, along with their overall antibiotic resistance patterns.
  • Researchers tested 305 clinical samples, isolating 100 strains and finding that E. faecalis made up 78% and E. faecium 22% of the isolates.
  • Results indicated that while all strains were susceptible to linezolid, E. faecium showed significant resistance to vancomycin and high rates of resistance to other antibiotics, highlighting the need for new strategies to tackle antimicrobial resistance.
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  • Helicobacter pylori (Hp) is linked to peptic ulcers, chronic gastritis, and gastric cancer, with certain pathogenicity genes contributing to more severe infection outcomes.
  • The study, conducted on patients at Shariati Hospital in Tehran, involved collecting gastric biopsy specimens from January to November 2015 to isolate and analyze Hp strains for specific virulence genes.
  • The results showed a 65.7% isolation rate of Hp strains, with notable differences in the presence of certain genes between patients with peptic ulcer disease (PUD) and gastric cancer (GC).
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Purpose: Lactic acid bacteria (LAB) have been associated with many beneficial effects in human digestive physiology. The aim of this study was to evaluate such effect, including attachment, antiproliferation and anti-pathogenic/antibacterial/antimicrobial properties of LAB isolated from healthy humans.

Methodology: Thirteen isolates, obtained from fecal samples of healthy individuals, were identified by phenotypic and molecular methods.

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Article Synopsis
  • The study investigates the role of specific lactic acid bacteria (LAB) in gastrointestinal health by isolating them from fecal samples and analyzing their antimicrobial properties against intestinal pathogens.
  • 72 different LAB species were identified, with about 40% showing antimicrobial activity, suggesting potential benefits for managing gut health.
  • The presence of bacteriocin encoding genes was low (only 6%), indicating more research is needed to fully understand their probiotic potential and the variety of genes in these bacteria.
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Antibacterial activity of Bifidobacterium species has been considered as an important probiotic property for development of human gut immunity. This study was conducted to assess the genotypes and antibacterial activities of the native Bifidobacterium isolates obtained from the human's breast milk and the feces of their paired infants. Fifty-six samples from twenty-eight mothers' milk and paired infants feces were collected and cultured.

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Enterococci are Gram positive and catalase- negative cocci that are found in the gastrointestinal tract of mammals and birds, and are readily isolated from soil, surface and waters. The aim of this study was to discriminate between Enterococcus isolates based on repetitive element sequence based -PCR (Rep-PCR) with the BOXA2R primer and their antibiotics profile. Enterococci isolates were obtained from 180 fecal samples.

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Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S.

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