Publications by authors named "Mette S Deleuran"

This is a case report of 51-year-old male patient with various symptoms including skin rashes, sensory disturbances, and non-cicatricial hair loss. Despite previous tests, the cause remained elusive until a dermatological examination revealed signs of syphilis. The patient's history, including his sexual relationships, became key in confirming the diagnosis, leading to treatment for neurosyphilis.

View Article and Find Full Text PDF

Atopic dermatitis (AD) is the most common dermatological diagnosis during pregnancy. Treatment of AD during pregnancy can be challenging, due to the unpredictable course and the fact that the therapy needs to be safe for both the mother and the fetus. Here we present an up-to-date appraisal of the literature on the treatment options available for AD in patients planning pregnancy, during pregnancy, and during breastfeeding.

View Article and Find Full Text PDF

Importance: Atopic dermatitis (AD) may affect academic performance through multiple pathways, including poor concentration associated with itching, sleep deprivation, or adverse effects of medications. Because educational attainment is associated with health and well-being, any association with a prevalent condition such as AD is of major importance.

Objective: To examine whether a childhood diagnosis of AD is associated with lower educational attainment.

View Article and Find Full Text PDF

The aim of this appraisal of the literature is to elucidate the effects of immunosuppressive and immunomodulating agents used to treat atopic dermatitis (AD) on risk factors for fertility, pregnancy, and breastfeeding. Negative side effects of the psychological and physical stresses associated to AD flairs and uncontrolled AD are discussed, in order to evaluate the consequences of abstaining from treatment. Research on pregnancies in Danish women suggests a tendency towards an increased use of topical steroids and ultraviolet light therapy during pregnancy, compared to before conception, confirming the need for these patients to receive treatment, as well as decreased use of systemic treatments, suggesting a tendency towards undertreatment in this patient population.

View Article and Find Full Text PDF

Background: Atopic dermatitis is characterized by chronic inflammation, which is a risk factor for atrial fibrillation.

Objective: To examine the association between hospital-diagnosed atopic dermatitis and atrial fibrillation.

Methods: Using linked population-based Danish registries, we identified persons with an inpatient or outpatient hospital diagnosis of atopic dermatitis during 1977-2013 and a comparison cohort individually matched to the atopic dermatitis cohort.

View Article and Find Full Text PDF

Objective: Atopic dermatitis (AD) is an inflammatory skin disorder with a childhood prevalence reaching 20%. An estimated 50% of patients have a life-long chronic course. The purpose of this study was to estimate the risk of first-time myocardial infarction (MI) in patients with AD compared with a general population cohort.

View Article and Find Full Text PDF

Background: Severe atopic dermatitis (AD) is a recurrent and debilitating disease often requiring systemic immunosuppressive treatment. The efficacy of cyclosporine A (CsA) is well proven but potential side effects are concerning. Several reports point at extracorporeal photopheresis (ECP) as an alternative treatment modality with few and mild side effects.

View Article and Find Full Text PDF

Severe atopic dermatitis has a profound effect on many aspects of the patient's life, and a combination of topical and systemic treatment is often necessary to control the disease. Systemic corticosteroids are rapidly effective, but should only be used short term for severe exacerbations because of their many long-term side effects. In chronic cases, starting another systemic immunosuppressant therapy while tapering off corticosteroids should be considered.

View Article and Find Full Text PDF

Morphea profunda is a rare disease that mainly affects young women and often has a progressive course with physical and psychological sequelae. The skin becomes sclerotic after an initial inflammatory reaction and joint contractures can develop. The aetiology is unknown.

View Article and Find Full Text PDF

A 7-year-old girl of Colombian descent was referred for diagnosis and treatment. She initially presented signs of universal itchy eczema in the spring of 2003. She responded to local treatment with topical steroids, but her symptoms rapidly re-emerged after discharge.

View Article and Find Full Text PDF

A case of childhood granulomatous perioral dermatitis (CGPD)/facial Afro-Caribbean childhood eruption (FACE) in a three year old boy from Madagascar is described. This disorder occurs predominantly in black children until puberty. It is a relatively uncommon condition of unknown aetiology characterized by a monomorphic, papular eruption around the mouth, nose and eyes.

View Article and Find Full Text PDF