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Publications by authors named "Metages Ayele Akinaw"

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Nephroprotective Effect of the Leaf Extract of remota Benth Against Gentamicin-Induced Nephrotoxicity in Swiss Albino Mice.
Metages Ayele Akinaw Suresh Kumar P Nair Rashed Edris Usure Bati Leta Abdo Kedir

J Exp Pharmacol

March 2024

Background: Drug-induced kidney injury was among the most common renal damages, from which gentamicin occupies around 25% of this injury. Gentamicin-induced renal damage is caused by increased free radicals with subsequent amplified inflammation. leaf extract has many phytochemicals with antioxidant activities, which may improve gentamicin-induced renal damage.

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Synopsis of recent research by authors named "Metages Ayele Akinaw"

  • - Metages Ayele Akinaw's research primarily focuses on the nephroprotective effects of natural extracts, specifically investigating their potential in counteracting gentamicin-induced nephrotoxicity in animal models! - The study highlights the significant role that antioxidants present in the leaf extract of a specific plant species, remota Benth, play in mitigating kidney damage caused by gentamicin, a common antibiotic associated with renal injury! - Akinaw’s findings suggest that integrating phytochemicals with antioxidant properties could provide a therapeutic approach to preventing drug-induced renal damage, emphasizing the importance of natural remedies in modern pharmacology!

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