[Early diagnosis of endometrial cancer].

The increasing morbidity rate of endometrial carcinoma has prompted the development of methods of examination suitable for the detection of asymptomatic carcinoma of the endometrium. Commercially available instruments for collection of specimens from the uterine cavity employ washing, aspiration or curettage techniques. Under clinical testing conditions, these instruments have been shown to have a high cytomorphological accuracy, namely 80%.

Follicle growth in the ovary of the rabbit after ovulation-inducing application of human chorionic gonadotropin.

The growth of tertiary follicles, i.e., the proliferation of cells in the stratum granulosum and in the capillary network of the theca interna, after injection of ovulation-inducing human chorionic gonadotropin (HCG), was investigated in the rabbit by means of autoradiographic and morphometric methods.

Diagnostic problems in differentiation of uterine sarcoma.

A 35 year old patient underwent radical abdominal hysterectomy for uterine malignancy, which was confined on curettage material. Histological examination revealed a wide range of atypical mesenchymal components. For further specification ultrastructural examination was performed.

[Invasive squamous cell carcinoma of the uterine cervix three years after cryosurgical treatment of a benign ectopy (author's transl)].

Report on a 33 years old para 4, who developed invasive squamous cell carcinoma of the cervix three years after cryosurgery for a large ectopy of the ectocervix. The carcinoma developed under an intact layer of normal superficial epithelium. The pap smears were negative at yearly intervals until a positive smear was obtained from a small iodinenegative area.

[Light and electronmicroscopic examinations on granulosa and theca of preovulatory and freshly ruptured follicles of human ovaries (author's transl)].

In a first paper, the structural and functional relationship of granulosa and theca of follicles during early development stages was reported. On the special question of whether and from which moment these two tissue formations are involved in the steroidbiosynthesis, our electronmicroscopic examinations have given a further insight to this. Neither the granulosa nor the theca folliculi of primordial, primary and secondary follicles show definite morphologic submicroscopic criteria of the steriodbiosynthesis.

[The optimal treatment of carcinoma in situ of the uterine cervix (author's transl)].

The results of treatment of carcinoma in situ of the uterine cervix in 380 patients seen between January 1, 1966 and December 31, 1973 are reported. There were 134 women age 40 or less. There were 246 patients age 40 or older.

[Light- and electronmicroscopic examinations on granulosa and theca of primordial-, primary-, secondary- and resting tertiary follicles of human ovaries (author's transl)].

Light- and electromicroscopic examinations were performed on granulosa and theca of primordial-, primary-, secondary- and resting tertiary follicles of human ovaries. These examinations were intended to clarify how far correlation exist between the structural components of the different tissue formations of the follicles and their determined functions. Remarkably many intraplasmatic filaments were found in the cytoplasm of granulosa cells of primordial-, primary- and secondary follicles.

[Therapy of ovarian stage-Ia carcinoma (review of 103 cases)].

103 cases of carcinoma of the ovary stage IA are presented, which have been operated upon at our clinic from 1944 to 1970. The 5 year cure rate of the 94 cases which had been treated until 1967 was 67%. 10 of the eleven patients who had been operated upon by preserving the opposite ovary -- in 4 cases additional radiotherapy was given -- were free of carcinoma after 5 years.