Publications by authors named "Messing-Juenger M"
Purpose: Our aim was to improve diagnosis and management of pseudotumor cerebri (PTC; also known as idiopathic intracranial hypertension) in children.
Methods: We performed a comprehensive analysis of epidemiology, diagnostic work-up, therapy, and clinical follow-up in 53 consecutive patients.
Results: We identified several important aspects to be considered in the management of these children.
Object: Over the past decade, a gravity-assisted valve (GAV) has become a standard device in many European pediatric hydrocephalus centers. Because past comparative clinical outcome studies on valve design have not included any GAV, the authors in this trial evaluated the early results of GAV applications in a pediatric population.
Methods: For a minimum of 2 years the authors monitored 169 of 182 hydrocephalic children who received a pediatric GAV at their first CSF shunt insertion (61.
The clinical manifestations of cerebral malformations are complex and vary from mild retardation to massive disabilities. A review of the literature suggests that the developmental outcome in these patients depends on the extension, location, and combination of such anomalies. However, the authors present the encouraging clinical course of a girl with a complex cerebral malformation.
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- Neurofibromatosis type I (NF1) is a common genetic disorder affecting the nervous system, with an elevated risk of developing serious tumors despite most patients being mildly affected.
- A case study of a 9-year-old girl illustrates the severe potential of NF1, as she rapidly developed a glioblastoma multiforme and was found to have a novel mutation in the NF1 gene.
- The girl's quick decline and death after diagnosis highlight the life-threatening aspects of NF1, raising questions about the effectiveness of routine MRI screenings in preventing such outcomes.
Article Synopsis
- Primary pseudotumor cerebri (PTC) in children is characterized by elevated cerebrospinal fluid (CSF) pressure without structural causes, often leading to serious outcomes like visual loss, and requires careful management.
- A study reviewing 12 pediatric cases revealed that most presented with headaches; treatment typically started with acetazolamide, with some requiring further options like furosemide, while a few had no symptoms until detected during eye exams.
- The study suggests that while acetazolamide is effective, young children may respond poorly to medical treatments, underscoring the need for surgical options if visual impairment progresses.
Osteogenesis imperfecta is an inherited collagenous disease. The mildest form may present with less severe findings, for example blue sclera, but can also lead to significant handicap such as deafness or multiple bone fractures. We describe an 11-month-old female in whom bilateral chronic subdural hematoma was the leading clinical presentation of osteogenesis imperfecta type I.
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