The Effect of Adjunctive Use of Hyaluronic Acid on Prevalence of in Subgingival Biofilm in Patients with Chronic Periodontitis: A Systematic Review.

() is a Gram-negative anaerobic bacterium that plays an important role in the development and progression of periodontitis. Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan that has previously demonstrated antibacterial potential in vitro against multiple bacterial species, including . The purpose of this systematic review is to evaluate the effectiveness of HA as an adjunctive topical antibacterial agent to non-surgical mechanical therapy of periodontitis in reducing the prevalence of in subgingival biofilms.

High molecular weight hyaluronic acid reduces the growth and biofilm formation of the oral pathogen .

Background: () is viewed as a keystone microorganism in the pathogenesis of periodontal and -implant diseases. Hyaluronic acid (HA) is believed to exert antimicrobial activity. The aim of this study is to assess the growth and biofilm formation of under HA and compare the effect of HA to that of azithromycin (AZM) and chlorhexidine (CHX).

High Molecular Weight Hyaluronic Acid Reduces the Expression of Virulence Genes fimA, mfa1, hagA, rgpA, and kgp in the Oral Pathogen .

() is a cornerstone pathogen in the development and progression of periodontal and peri-implant tissue destruction. It is capable of causing dysbiosis of the microbial biofilm and modulation of the host immune system. Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan found in all living organisms.