A systemic review of rubidium-82 PET contrasted with 99mTc-MIBI SPECT for imaging coronary artery disease.

Background: 99mTc-sestamibi single photon emission tomography (SPECT) method is widely used for imaging coronary artery disease (CAD). 82-Rubidium-PET is an alternative method that can be used to perform the same purpose.

Purpose/aim: This study aims to determine whether 82-Rubidium-PET can offer extra value over 99mTc-sestamibi SPECT in imaging CAD.

Amygdala and subregion volumes are associated with photoperiod and seasonal depressive symptoms: A cross-sectional study in the UK Biobank cohort.

Although seasonal changes in amygdala volume have been demonstrated in animals, seasonal differences in human amygdala subregion volumes have yet to be investigated. Amygdala volume has also been linked to depressed mood. Therefore, we hypothesised that differences in photoperiod would predict differences in amygdala or subregion volumes and that this association would be linked to depressed mood.