Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells.

Background & Aims: Liver macrophages fulfill various homeostatic functions and represent an essential line of defense against pathogenic insults. However, it remains unclear whether a history of infectious disease in the liver leads to long-term alterations to the liver macrophage compartment.

Methods: We utilized a curable model of parasitic infection invoked by the protozoan parasite Trypanosoma brucei brucei to investigate whether infection history can durably reshape hepatic macrophage identity and function.

Psychometric Properties of the Persian Translation of the 12-Item Utah Photophobia Symptom Impact Scale Questionnaire.

To translate the the Utah Photophobia Symptom Impact Scale-12 questionnaire into Persian and assess the psychometric aspects to check its validity and reliability based on the Rasch modelling method. Translation and cultural adjustment of the English language UPSIS-12 questionnaire to Persian was undertaken. A total of 61 patients with complaints of photophobia participated in evaluating validity and reliability aspects.

Assessment of radiation exposure risks in patients undergoing elastic stable intramedullary nailing: Insights from intraoperative fluoroscopy.

Introduction: Elastic stable intramedullary nailing (ESIN) is a well-defined and appropriate treatment of choice for long bone fractures. Despite its benefits, the risk of cancer from imaging devices is of particular concern for younger adults. So, this survey was conducted to estimate the doses administered to patients undergoing ESIN of long bone fractures utilizing a 2-dimensional (2D) C-arm fluoroscopy machine during surgery, as well as the carcinogenic risk associated with the use of the machine.

The association between ocular biometric components and corneal aberrations.

Clinical Relevance: Evaluating factors affecting corneal higher-order aberration component has a very important role in interpreting the characteristics of the formed image on the retina.

Background: To determine the relationship between ocular biometric components and corneal higher-order aberrations in an elderly population.

Methods: This report is related to a subsample of the Tehran Geriatric Eye study (TGES), a population-based cross-sectional study that was conducted on individuals aged 60 years and above in Tehran city, Iran using multistage stratified random cluster sampling.

Transfer of the Long Head Biceps Tendon to Conjoined Tendon in Proximal Humerus Fractures with Cleavage or Comminution at the Bicipital Groove.

Objective: To evaluate the clinical and radiographic findings of long head biceps tendon (LHBT) transfer in traumatic proximal humeral fractures with the biceps groove breakage or comminution.

Methods: In this interventional study, subjects surveyed in terms of shoulder function, clinical signs of LHBT tendinitis, radiographic signs of transferred biceps as a possible depressor of the shoulder, and mechanical changes of the scapula. Data were analyzed in SPSS version 21.

Effect of Casein Phosphopeptide Amorphous Calcium Phosphate Conditioning on Microtensile Bond Strength of Three Adhesive Systems to Deep Dentin.

Objectives: This study aimed to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) on microtensile bond strength of three adhesive systems to deep dentin.

Materials And Methods: In this in vitro study, the occlusal surface of 30 sound human third molars was sectioned at 2 mm below and above the cementoenamel junction. The samples were randomly divided into three groups of OptiBond Solo Plus, G-Bond, and Clearfil SE Bond.

Outcome after Surgical Management of Acetabular Fractures: A 7-Year Experience.

Objective: To determine the functional and radiologic results of surgical treatment in patients with acetabular fractures.

Methods: This was a retrospective cross-sectional study. We retrospectively reviewed medical records of patients operatively treated acute acetabular fractures at a level I trauma center (Shahid Rajaee) and an orthopedic center (Shahid Chamran) both in southern Iran (Shiraz) with minimally 1 year follow up over a period of 7 years from April 2009 to March 2016.

Anatomical Variations of Ostiomeatal Complex in CBCT of Patients Seeking Rhinoplasty.

Statement Of The Problem: Anatomic variation can potentially impact the surgical safety.

Purpose: The purpose of this cross-sectional study was to assess the prevalence of ostiomeatal complex variations based on cone beam computed tomography (CBCT) images of the patients seeking rhinoplasty.

Materials And Method: In this cross-sectional study, CBCT images of 281 patients including 153 female and 128 male with Mean±SD age of 26.

End plate disproportion and degenerative disc disease: a case-control study.

Study Design: Case-control.

Purpose: To determine whether a disproportion between two neighboring vertebral end plates is associated with degenerative disc disease.

Overview Of Literature: Recently, it has been suggested that disproportion of the end plates of two adjacent vertebrae may increase the risk of disc herniation.

Disproportion of end plates and the lumbar intervertebral disc herniation.

Background Context: It is suggested that the shape of the vertebral end plates may play a role in the development of abnormalities in the intervertebral disc. On midsagittal magnetic resonance images of the spine in patients with lumbar intervertebral disc herniation, a notable disproportion frequently exists between the end plates of two vertebrae to which the disc is attached. There is apparently no study in the literature examining possible association of this disproportion with development of disc herniation.

Complex fractures of the tibia and femur treated with static interlocking intramedullary nail.

Background: Reamed interlocking intramedullary nailing is considered the gold standard treatment for complex fractures of the femoral and tibial shaft. There has been some controversies about dynamization of statically locked nails, and some authors recommended routine dynamization for promotion of healing. This study aims to evaluate treatment of complex fractures in tibia and femur with static interlocking intramedullary nail method.

Unilateral pulmonary changes in the chest X-ray in sarcoidosis.

Unilateral or segmental pulmonary involvement in sarcoidosis is rare. So is unilateral lymphadenopathy, and the combination can cause considerable difficulty in diagnosis if it is present when the patient first attends. Sarcoidosis should be considered in the differential diagnosis of unilateral lung lesions.