Publications by authors named "Meryl Antony"

Article Synopsis
  • Darier disease (DD) is a rare genetic skin condition primarily documented through case reports, prompting a study to systematically examine its histopathologic features in skin biopsies over 12 years.* -
  • The study reviewed biopsies from 16 patients, primarily in their 30s, revealing common symptoms like hyperpigmented papules and plaques, with notable histological features including suprabasal acantholytic clefts and various unusual patterns.* -
  • The study emphasizes the importance for pathologists to recognize the diverse histopathological variations of DD, particularly in atypical cases, while acknowledging its limitation due to a small sample size.*
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Article Synopsis
  • Lichen planus (LP) and lichen sclerosus (LS) are common skin conditions affecting the vulva, but they can be challenging to diagnose due to different appearances and biopsy sizes.
  • This study reviewed cases from 2012 to 2022, analyzing clinical details like age, symptoms, and biopsy results to differentiate between LP and LS.
  • The findings revealed distinct clinical features and histopathological characteristics for each condition, highlighting that while classic LS is easier to identify, some atypical cases can resemble LP, emphasizing the importance of careful examination for accurate diagnosis.
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Cutaneous tuberculosis is known for its varied presentations, especially in the setting of immunosuppression. Clinical manifestations can be modified by the site of involvement as well as the type of cutaneous tuberculosis in a particular patient. Although cutaneous tuberculosis only accounts for a small percentage (1-2%) of extrapulmonary cases, it is encountered fairly frequently in dermatology practice in an endemic country like India.

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Dermatophytosis due to the complex is being increasingly reported across India. Reports of therapeutic failure have surfaced recently, but there are no clinical break points (CBP) or epidemiological cutoffs (ECVs) available to guide the treatment of dermatophytosis. In this study, a total of 498 isolates of the complex were collected from six medical centers over a period of five years (2014 to 2018).

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Introduction: Henoch-Schönlein Purpura (HSP; IgA vasculitis), the most common vasculitis of childhood, has a wide spectrum of clinical manifestations ranging from palpable purpura with abdominal pain and arthritis to the more morbid renal involvement.

Aims And Objectives: To study and correlate the clinical presentation, laboratory values, skin and renal histopathology and immunofluoroscence findings in HSP.

Material And Methods: A total of 44 cases of HSP from March 2011 to February 2014 were studied for the above features along with their clinical outcomes.

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Background: Papulonecrotic tuberculid (PNT) is said to be a hypersensitivity reaction to M. tuberculosis. Some reports indicate that organisms are demonstrable by polymerase chain reaction (PCR).

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Objectives: Diagnosis of scarring alopecias (SAs) are challenging, especially when lesions late in the process of development are met with. There is a paucity of literature that profiles the role of histopathology in unscrambling this puzzle, especially in Indian patients. Our aim is to review the histological features of SA in Indian patients and attempt to assign a specific diagnosis.

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Background: Follicular Mycosis Fungoides (FMF) is an under-recognized disease in India. Its clinical mimics include Hansen's disease and Sarcoidosis.

Aims: To describe the clinical and pathological features of FMF.

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We report a case with abdominal complications of clofazimine treatment which included blackish discolouration of the lymph nodes, omentum and peritoneum. A 44-year-old female with lepromatous leprosy and a history of adverse reaction to clofazimine 2 years previously, presented with rectosigmoid junction adenocarcinoma. Laparotomy revealed an inoperable tumour with pigmentation of the bowel, serosa and peritoneum.

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