Topical prebiotics/postbiotics and PRURISCORE validation in atopic dermatitis. International study of 396 patients.

To investigate the efficacy and tolerability of a cream (Rilastil Xerolact PB) containing a mixture of prebiotics and postbiotics, and to validate the PRURISCORE itch scale in the management of atopic dermatitis. The study is based on 396 subjects of both sexes in three age groups (i.e.

The effect of dietary intake of coenzyme Q10 on skin parameters and condition: Results of a randomised, placebo-controlled, double-blind study.

Coenzyme Q10 (CoQ10) is a natural constituent of foods and is also often used in both functional foods and supplements. In addition, it is a common ingredient of cosmetics where it is believed to reduce the signs of skin ageing. However, the existing data about the effect of dietary intake of CoQ10 on skin parameters and condition are scarce.

Management of moderate to severe plaque psoriasis in pregnancy and lactation in the era of biologics.

Psoriasis is not uncommon in the reproductive years and therefore in pregnant patients. There are limited data about the impact of psoriasis on the course and prognosis of pregnancy and about the impact of pregnancy on the course of psoriasis. Usually the disease improves during pregnancy and patients experience worsening between 4 and 6 weeks after delivery.

Prognostic factors in patients with localized primary cutaneous melanoma.

The clinical and histopathological characteristics that predict the outcomes of patients with melanoma have been studied for more than four decades. Increasingly more melanoma patients are being included in prospectively collected databases and our understanding of the biology of melanoma is improving. Therefore, the melanoma staging system is constantly being revised.

Time course and pattern of metastasis of cutaneous melanoma differ between men and women.

Background: This study identified sex differences in progression of cutaneous melanoma.

Methodology/principal Findings: Of 7,338 patients who were diagnosed as an invasive primary CM without clinically detectable metastases from 1976 to 2008 at the University of Tuebingen in Germany, 1,078 developed subsequent metastases during follow up. The metastatic pathways were defined in these patients and analyzed using the Kaplan-Meier method.

Sex differences in survival of cutaneous melanoma are age dependent: an analysis of 7338 patients.

This study identified sex differences in clinical presentation and survival for primary cutaneous melanoma without clinical evidence of metastasis at diagnosis from 1976 to 2008 in southern Germany. Melanoma-specific survival curves and estimated survival probabilities were generated using the Kaplan-Meier method. Multivariate survival analyses were carried out using the Cox modeling.

Lichen striatus in a child after immunization. A case report.

Lichen striatus is a self-limited, lichenoid eruption particularly common in children. The lesions are located on extremities and less commonly on the trunk, and they follow the developmental lines of Blaschko. The etiology of lichen striatus is as yet unknown.