Publications by authors named "Merve Sekizkardes"

Application of botulinum toxin A (BoNT-A) into the muscles of the head and neck area has become a widespread and reliable treatment modality for chronic migraine. The mechanism of action for BoNT-A is the inhibition of acetylcholine and local nociceptive peptide release at the terminal nerve endings. Cranial sutures have the highest concentration of nociceptive structures; therefore BoNT-A injection into the suture lines - as opposed to head and neck muscles - has been proposed for the treatment of chronic migraine.

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Here, we report a case of a 30-year-old man with a diagnosis of complex shoulder instability, who was treated successfully by pectoralis major transfer following a series of failed instability correction surgeries. The patient was admitted to our outpatient clinic with an approximately 6-year history of chronic shoulder instability following several failed operations, including open Bankart repair, open capsular plication and Bankart repair, open capsule repair, arthroscopic Bankart repair, and Bristow-¬Latarjet procedure. Physical examination revealed persistent shoulder pain, weakness, and a limited range of motion.

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The developments in technology have improved access to the use of musculoskeletal ultrasound (MSUS) in different clinical settings. Accordingly, MSUS has been applied to a wide range of musculoskeletal problems including inflammatory and degenerative diseases, sport injuries, and regional pain syndromes both for clinical practice and research. In this report, the authors aimed to globally examine the publications on MSUS among different specialties, countries, and topics.

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The treatment of chronic migraine headache is quite challenging and new alternatives are still being explored for its management. Onabotulinum toxin A (BoNT-A) applied into extracranial muscles has been shown to inhibit the release of acetylcholine and local nociceptive peptides at the sensory nerve endings. As the highest concentration of extracranial pain fibers are located at/nearby the sutures, extracranial applications of BoTN-A are suggested to be performed to sutures rather than into the head and neck muscles in the treatment of chronic migraine.

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Drug addiction has become an important problem worldwide, and the number of heroin users has been rapidly increasing. There are serious complications related to intravenous drug use. Sharing injectors and using them multiple times cause septic and infective complications.

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Article Synopsis
  • * This study analyzed 260 stroke patients to explore the links between mental and functional status and LUTD symptoms using various questionnaires.
  • * Results showed that a significant majority of patients experienced LUTD, with those affected displaying notably lower cognitive and functional scores, highlighting the need for attention to bladder issues in stroke rehabilitation.
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