Publications by authors named "Merve Guner Oytun"

Background: For hospitalized adults, it is important to initiate the early reintroduction of oral food in accordance with nutrition support team guidelines. The aim of this study was to develop and validate a machine learning-based algorithm that predicts the early termination of medical nutritional therapy (the transition to oral feeding).

Methods: This retrospective cohort study included consecutive adult patients admitted to the Hacettepe hospital (from 1 January 2018 to 31 December 2022).

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Generating memory T cell responses besides humoral immune responses is essential when it comes to the efficacy of a vaccine. In this study, the presence of memory T cell responses after aluminum-adjuvanted inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac) in seronegative and seropositive elderly individuals were examined. CD4 and CD8 memory T cell proliferation and IFN-γ production capacities were evaluated.

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Objectives: Frailty is a dynamic process. Frailty in the baseline, discharge, and post-discharge are important in the management of patients. We aimed to see how hospitalization affects frailty and to evaluate its effects on health outcomes.

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Background: The aim of this study is to validate the Turkish version of the 5-minute cognitive test (FCT) in a geriatric population.

Materials And Method: In total, 61 participants aged ≥65 years with normal cognitive functions, mild cognitive impairment (MCI), and early stage dementia were included. The FCT was compared to the standardised Mini Mental State Examination (MMSE) and the Qmci-TR (quick mild cognitive impairment) test.

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Background: Recognizing frailty had a great importance in countries with an increasing geriatric population. The study aims to evaluate the reliability and validation of the Gérontopôle frailty screening tool (GFST), which was developed to screen frailty in the community-dwelling older adults, for the Turkish population.

Methods: In this crosssectional study, participants who applied to the geriatrics outpatient clinic of a university hospital were included.

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In the COVID-19 pandemic, due to the difficulties in patients' applications to health centres, changes have occurred in the places of death of older adults. It is aimed to investigate the change in the places of death of older adults in Turkey, which is one of the countries most affected by the pandemic. Patients admitted to the geriatric outpatient clinic of a university hospital from 01.

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Background And Purpose: Cognitive impairment is one of the main risk factors for falls, and hence it commonly coexists with balance issues. Frailty and sarcopenia are intertwined and prevalent in dementia, and are closely related to falls. We aimed to determine the relationships of the fall risk with balance disturbances, sarcopenia, and frailty in mild-to-moderate Alzheimer's disease (AD).

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Purpose: We aimed to investigate the effects of colchicine, an important anti-inflammatory agent, on cognitive functions in a geriatric population diagnosed with gout or osteoarthritis by comparing it to non-colchicine users.

Methods: 138 geriatric patients (67 colchicine users and 71 non-users) were enrolled. Within comprehensive geriatric assessment (CGA), cognitive status assessment via Mini-Mental State Examination test (MMSE), Quick Mild Cognitive Impairment Screening test (Qmci), clock drowning test (CDT), and digit span tests were performed.

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Background: The most important disadvantage of surgical mask usage is that it can aversely affect communication. This study aimed to evaluate the possible effects of face masks on the cognitive test performance of older adults.

Methods: A total of 198 geriatric patients were enrolled after applying the exclusion criteria.

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Article Synopsis
  • This study explored how shear-wave elastography (SWE) can help evaluate muscle quality and its relationship with muscle strength and mass.
  • Conducted with 129 patients aged 18-87, the study included various assessments like muscle strength measured through handgrip strength, muscle mass via ultrasound, and muscle quality using SWE.
  • Results showed that patients with lower handgrip strength had significantly lower SWE measurements, suggesting that SWE can be an effective tool to predict muscle strength; however, more research is needed to validate the findings.
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Objectives: Osteosarcopenic obesity (OSO; also known as adiposity) is the combination of three critical conditions. This study aimed to define OSO using muscle ultrasonography (US), and examine the relationship between OSO and frailty compared with its constituent components.

Methods: A total of160 geriatric patients with a body mass index of ≥30 were enrolled in the study.

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Article Synopsis
  • - The study compared the Mini Nutritional Assessment-Short Form (MNA-SF) and Long Form (MNA-LF) to see which better predicts mortality in geriatric outpatients over 7 years.
  • - Out of 209 patients followed, 36.8% died within the study period, with MNA-SF showing a significant association with mortality across various follow-up periods, though MNA-LF excelled in predicting short-term mortality (6-month and 1-year).
  • - Both assessment tools effectively predict mortality risk, with MNA-SF offering valuable information for identifying patients at risk for malnutrition, emphasizing the need for regular screening in older adults to enable early interventions.
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Objectives: This study aimed to provide data about the role of muscle ultrasound (US) to predict sarcopenia.

Methods: A total of 313 geriatric outpatients (age ≥65 y) were enrolled in the study. After a comprehensive geriatric assessment, anthropometric measurement and handgrip strength (HGS) data were obtained and a bioelectrical impedance analysis was performed.

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Background: Dysphagia is a geriatric syndrome. Changes in the whole body that occur with aging also affect swallowing functions and cause presbyphagia. This condition may progress to oropharyngeal and/or esophageal dysphagia in the presence of secondary causes that increase in incidence with aging.

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Background: Sars-CoV-2 infection influences older individuals at the forefront, and there is still limited data on the COVID-19 vaccine response in the geriatric population. This study aimed to assess antibody response after vaccination with SARS-CoV-2 inactivated vaccine and examine possible factors affecting this response in a geriatric population.

Methods: individuals who have been on at least the 28th day after the second dose of the COVID-19 vaccine were included.

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Purpose: Geriatrician numbers are increasing year by year in Turkey. We aimed to obtain information on licensed geriatricians, trainees, and board of directors of the societies in Turkey and compare this information with other countries' data.

Methods: The study was conducted as a cross-sectional study.

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Purpose: Frailty, orthostatic blood pressure changes (OBPC), and orthostatic intolerance syndrome (OIS) are common in geriatric patients. However, the results of the studies evaluating the relationship between these entities are discordant. We aimed to investigate the association between frailty and OIS with or without OBPC.

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Background: The aim of the study is to reveal the contribution of complete response (CR) to treatment to overall survival (OS) in patients with unresectable metastatic colorectal cancer. In addition, to evaluate progression-free survival (PFS) in patients who attained CR to treatment and to examine the clinicopathologic features of the patient group with CR.

Methods: This article is a retrospective chart review.

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We carefully studied the article titled "A practical laboratory index to predict institutionalization and mortality - an 18-year population-based follow-up study" written by Heikkilä et al. and published in BMC Geriatrics on 25 February 2021 with great interest. We would like to make some comments regarding this article and tool.

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End-of-life care has become an important public health issue in recent years. Place of death is a major component of end-of-life care. Despite attempts to improve end-of-life care, there has not been published any data about place of deaths in Turkey.

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Aim: Decision- making of the treatment of colon cancer for the older patients becomes more complicated in consequence of comorbidities and geriatric syndromes, most importantly frailty. In the present study, we aimed to investigate whether there is a difference between tumour characteristics, treatment choices, and outcomes between the younger and older adults.

Method: The patients who were diagnosed with colorectal carcinoma in our centre between 2010 and 2015 included.

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Aim: In recent years, the prognostic and predictive value of primary tumor localization in colon cancer has become increasingly important. This study aimed to retrospectively analyze the effect of colon cancer tumor localization on progression-free survival, overall survival, and response to treatments and present real-life data.

Method: Retrospective evaluation was made of 465 patients who were diagnosed with metastatic colorectal carcinoma between 2010 and 2015 in our clinic.

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Background: Allograft biopsy that is done as indicated by clinical and laboratory clues about graft rejection provides a definitive diagnosis. Noninvasive methods that may be useful for predicting or diagnosing rejection are important for early diagnosis of possible rejection.

Purpose: The aim of this study is to investigate the relationship between changes in shear wave velocity (SWV) values and renal allograft kidney biopsy findings.

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