The Ameliorative Effects of Pycnogenol on Liver Ischemia-Reperfusion Injury in Rats.

Objectives: Pycnogenol (PYC), a standardized extract from the bark of , consists of different phenolic compounds. PYC has shown to have protective effects on chronic diseases such as diabetes, asthma, cancer, and immune disorders. The aim of this study was to determine the effects of PYC against the DNA damage and biochemical changes in blood, liver, and lung tissues of ischemia-reperfusion (IR)-induced Wistar albino rats.