Publications by authors named "Merredith R Lowe"

Article Synopsis
  • The study reviews cognitive outcomes in patients with mesiotemporal epilepsy (mTLE) after undergoing laser interstitial thermal therapy (LiTT), focusing on changes in neuropsychological performance.
  • It analyzed 26 patients, comparing their mental abilities before and after surgery across various cognitive areas, revealing improvements in learning, memory, processing speed, and executive functioning, particularly in both dominant and nondominant hemisphere patients.
  • The findings suggest that LiTT results in a lower rate of language or verbal memory decline compared to traditional surgeries, highlighting the need for future research to examine a broader range of cognitive outcomes post-surgery.
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Objective: We aimed to identify risk factors for seizures after intracerebral hemorrhage, and to validate the prognostic value of the previously reported CAVE score (0-4 points: cortical involvement, age <65, volume >10 mL, and early seizures within 7 days of hemorrhage).

Patients And Methods: Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) was a prospective study of spontaneous intracerebral hemorrhage. We included patients who did not have a prior history of seizure and survived to discharge.

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Objective: To identify features of ablations and trajectories that correlate with optimal seizure control and minimize the risk of neurocognitive deficits in patients undergoing laser interstitial thermal therapy (LiTT) for mesiotemporal epilepsy (mTLE).

Methods: Clinical and radiographic data were reviewed from a prospectively maintained database of all patients undergoing LiTT for the treatment of mTLE at the University of Miami Hospital. Standard preoperative and postoperative evaluations, including contrast-enhanced magnetic resonance imaging (MRI) and neuropsychological testing, were performed in all patients.

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Microwave ovens are often recommended as a safe cooking alternative for persons with epilepsy. We report four patients who suffered serious burns to their hands while handling microwave-heated liquids during a complex partial seizure (CPS). Injuries were due to the contact of the skin with a very hot container.

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We reviewed the incidence of aspiration pneumonia secondary to seizures in three populations of patients with chronic epilepsy: 733 outpatients seen in an Epilepsy Foundation clinic; 806 adult patients admitted to two university video telemetry units; and 95 institutionalized, profoundly retarded adult patients with chronic epilepsy. Two of the 733 adults who had seizures in the outpatient setting and 2 of the 806 patients who had one or more epileptic seizures in the telemetry units developed aspiration pneumonia. In the 95 institutionalized patients, there were 17 instances of aspiration pneumonia after a generalized seizure and 32 instances of aspiration unrelated to seizures over a 12-month period.

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We reviewed 824 video-EEG telemetry requests of institutionalized patients with epilepsy, searching for evaluations of "new seizure types" identified by staff (caregivers, teachers, therapists, LPNs, RNs). Of the 63 newly identified "seizure types," epilepsy was confirmed in 4 (6.3%); 59 represented nonepileptic events.

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Serious seizure-related burns are reportedly common in cultures that use ground fire for cooking, heating, or ceremonial purposes. The seriousness of injuries in these cases has been ascribed to the reluctance of bystanders to assist individuals having a seizure either because of fear of contagion (Africa, New Guinea highlands) or because of fear of revenge by the occult (Haiti). We report four Haitian patients who fell into open fires during an epileptic seizure in religious gatherings.

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