Publications by authors named "Merna Wagih Youssef"
The role of creatine kinase in distinguishing generalized tonic-clonic seizures from psychogenic non-epileptic seizures (PNES) and syncope: a retrospective study and meta-analysis of 1300 patients.
Ramy Abdelnaby Anas Elgenidy Jan Heckelmann Mahmoud Mostafa Bedewy Ahmed Samy Shabib Merna Wagih Youssef
Neurol Res Pract
October 2023
Article Synopsis
- A study aimed to determine if serum creatine kinase (CK) levels could help differentiate between epileptic seizures, psychogenic non-epileptic seizures (PNES), and syncope, since detailed reports of these events are often unavailable.
- The results of a cohort study with 202 patients found that CK levels were significantly higher in patients with epileptic seizures 48 hours after the event compared to those with syncope.
- A meta-analysis involving 1,086 patients reinforced these findings, indicating that CK levels were notably higher in epileptic seizures compared to PNES and syncope, thus suggesting CK could be a useful diagnostic marker.
Because of the insidious character and variations in presenting symptoms, Charcot-Marie-Tooth (CMT) disease is challenging to diagnose in children. Diagnosis is based on clinical and nerve conduction studies, as well as genetic examination. Therefore, competent nerve imaging techniques and non-invasive alternatives to nerve conduction studies are a necessity, especially in children.
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