Publications by authors named "Merkle A"

Background: Acetabular subchondral cysts are commonly identified signs of joint degeneration and arthritis. This pathology is generally considered a relative contraindication for hip preservation surgery.

Purpose: To investigate the effect of arthroscopic bone grafting for the treatment of acetabular subchondral cysts.

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  • Researchers are exploring a method to lower the cost of III-V solar cells by detaching them from their growth substrate, allowing for the reuse of the substrate to produce multiple cells.
  • The study focuses on smoothing the faceted surfaces left on GaAs(100) substrates after spalling to enable the growth of high-quality solar cells.
  • The smoothing process can be influenced by the choice of epilayer material and the introduction of impurities or dopants, which significantly affect the smoothness and rate of surface improvement.
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  • A 20-year-old man with a complex medical history involving Legg-Calve-Perthes disease and hip issues underwent multiple surgeries including arthroscopic femoroplasty and allografting.
  • The procedures aimed to repair fragmented bone and improve hip function, culminating in a valgus-producing derotational femoral osteotomy and periacetabular osteotomy.
  • At the one-year follow-up, the patient showed complete healing of the femoral head and successfully returned to his active lifestyle, marking a first in the use of arthroscopic allografting for this condition.
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Background: Non-compressible abdominal hemorrhage (NCAH) is the leading cause of potentially preventable deaths in both civilian and military austere environments, and an improvement in mortality due to this problem has not been demonstrated during the past quarter century. Several innovations have been developed to control hemorrhage closer to the point of injury.

Objective: This review assessed NCAH interventions in civilian and military settings, focusing on austere environments.

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Sprint and jump performances represent performance-determining parameters in individual and team sports. Fluctuations in performance depending on the daytime raise the question of the best time to train and compete. Given the scarce research on females, this study aimed to analyze the influence of daytime on sprint and jump performances and to investigate whether the performance difference is related to the chronotype.

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Cartilage injuries are common and may predispose to early accelerated osteoarthritis. Magnetic resonance (MR) imaging is critical in the detection and characterization of acute and chronic cartilage injuries. Several surgical approaches including microfracture, osteochondral allografting, autologous osteochondral transfer system, and autologous chondrocyte implantation have been developed to treat cartilage lesions.

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Musculoskeletal injections serve a variety of diagnostic and therapeutic purposes, with ultrasonography (US) guidance having many advantages: no ionizing radiation, real-time guidance, high spatial resolution, excellent soft tissue contrast, and the ability to identify and avoid critical structures. Sonography can be cost effective and afford flexibility in resource-constrained settings. This article describes US-guided musculoskeletal injections relevant to many radiology practices and provides experience-based suggestions.

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The management of non-compressible torso hemorrhage in military austere/remote environments is a leading cause of potentially preventable death in the prehospital/battlefield environment that has not shown a decrease in mortality in 26 years. Numerous conceptual innovations to manage non-compressible torso hemorrhage have been developed without proven effectiveness in this setting. This scoping review aims to assess the current literature to define non-compressible torso hemorrhage in civilian and military austere/remote environments, assess current innovations and the effectiveness of these innovations, assess the current knowledge gaps and potential future innovations in the management of non-compressible torso hemorrhage in civilian and military austere/remote environments, and assess the translational health science perspective of the current literature and its potential effect on public health.

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Fatty masses are common and may be encountered in the foot and ankle. In some cases, normal subcutaneous fat may be mistaken for a discrete mass. The aim of this study was to evaluate the common finding of prominent subcutaneous fat at the medial midfoot resembling a lipoma and to determine the prevalence of this pseudolesion by applying a series of potential size cutoff criteria.

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Case: Longitudinal follow-up of a 53-year-old woman with osteogenesis imperfecta (OI) Type III and concurrent bilateral distal radius fractures is reported. She had a right-sided displaced fracture and a left-sided minimally displaced fracture. Operative management of the displaced fracture showed adequate healing in 10 weeks.

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The lower extremity is the most frequently injured body region to mounted soldiers during underbody blast (UBB) events. UBB events often produce large deformations of the floor and subsequent acceleration of the lower limb that are not sufficiently mitigated by the combat boot, leaving the calcaneus bone vulnerable to injury. Biomechanical experiments simulating UBB loading scenarios were conducted in a laboratory environment using isolated postmortem human subject (PMHS) leg components.

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This is the first of an ongoing series to provide a background into reading medical research literature for the SOF medic.

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Remote and austere medicine can be challenging when caring for healthy individuals and requires ingenuity when managing patients with unexpected, complex disease processes, whether acute or chronic. We report the case of an adult male who presented to an isolated clinic setting with acute exacerbation of chronic liver disease. Medical management was complicated by limited transportation resources, both for supplies and patient movement.

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It is critical to understand the relationship between under-body blast (UBB) loading and occupant response to provide optimal protection to the warfighter from serious injuries, many of which affect the spine. Previous studies have examined component and whole body response to accelerative based UBB loading. While these studies both informed injury prediction efforts and examined the shortcomings of traditional anthropomorphic test devices in the evaluation of human injury, few studies provide response data against which future models could be compared and evaluated.

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MRI sensitivity for diagnosis and localization of early myocarditis is limited, although it is of central clinical interest. The aim of this project was to test a contrast agent targeting activated platelets consisting of microparticles of iron oxide (MPIO) conjugated to a single-chain antibody directed against ligand-induced binding sites (LIBS) of activated glycoprotein IIb/IIIa (= LIBS-MPIO). Myocarditis was induced by subcutaneous injection of an emulsion of porcine cardiac myosin and complete Freund's adjuvant in mice.

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Limited data exist on the injury tolerance and biomechanical response of humans to high-rate, under-body blast (UBB) loading conditions that are commonly seen in current military operations, and there are no data examining the influence of occupant posture on response. Additionally, no anthropomorphic test device (ATD) currently exists that can properly assess the response of humans to high-rate UBB loading. Therefore, the purpose of this research was to examine the response of post-mortem human surrogates (PMHS) in various seated postures to high-rate, vertical loading representative of those conditions seen in theater.

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In the past few years, dynamic computed tomography (CT) approaches or uninterrupted acquisitions of deforming materials have rapidly emerged as an essential technique to understand material evolution, facilitating in situ investigations ranging from mechanical deformation to fluid flow in porous materials and beyond. Developments at synchrotron facilities have led this effort, pointing to the future of the technique. In the laboratory, recent developments at TESCAN XRE have made it possible to image, reconstruct and inspect dynamic processes in the laboratory with a temporal resolution below 10 s, meaning that an entire acquisition from 0 to 360° is completed within 10 s.

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Dancers exert tremendous stresses on the lower extremities rendering them prone to injuries that can curtail training and performance. The goal of this study was to evaluate clinical improvement in a population of elite dancers following treatment with ultrasound-guided platelet-rich plasma (PRP) injections of various lower extremity sites by assessing when they were able to return to dance. Nineteen dancers (13 female, 6 male; ages 15 to 42) were treated between 2009 and 2016 at sites that included: hamstring tendon (1), proximal iliotibial band (1), patellar tendon (3), posterior tibial tendon (5), peroneus brevis tendon (3), plantar fascia (3), and the first metatarsophalangeal (MTP) joint capsule (3).

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Objective: The concept of integrative oncology (IO) comprising guideline-oriented standard and add-on complementary medicine has gained growing importance. The Anthroposophic-integrative Cancer Centre (CC) at the hospital Gemeinschaftskrankenhaus (GKH) in Berlin has been implementing IO concepts during recent years. Furthermore, it is a certified CC and has been annually audited by national cancer authorities since 2012.

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: Despite improvement of tumor response rates, targeted therapy may induce toxicities in cancer patients. Recent studies indicate amelioration of adverse events (AEs) by add-on mistletoe ( L., VA) in standard oncological treatment.

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