Design of poly-l-glutamic acid embedded mesoporous bioactive glass nanospheres for pH-stimulated chemotherapeutic drug delivery and antibacterial susceptibility.

In this research, a core-shell type pH-responsive poly-l-glutamic acid embedded mesoporous bioactive glass nanospheres (MBAG/PLGA) was designed via aminosilane functionalization of MBAG using 3-aminopropyltriethoxysilane (APTES). The formation of MBAG/PLGA was well dispersed in an aqueous medium and demonstrated high drug loading efficacy and enhanced drug delivery rate. Daunomycin (DAN) was considered as a model chemotherapeutic drug for loading and release study.

Direct electrochemical reduction of hematite decorated graphene oxide (α-FeO@erGO) nanocomposite for selective detection of Parkinson's disease biomarker.

An unusual approach is reported herein to fabricate magnetic hematite (α-FeO) decorated electrochemically reduced graphene oxide (α-FeO@erGO) nanocomposite. The method utilizes direct electrochemical reduction of self-assembled, ex-situ synthesized α-FeO anchored GO to erGO (α-FeO@erGO) on glassy carbon electrode (GCE) for selective detection dopamine (DA), an important biomarker of Parkinson's disease. The formation of α-FeO@erGO/GCE has been confirmed by XPS and Raman spectroscopy.

Exploration of Wedelia chinensis leaf-assisted silver nanoparticles for antioxidant, antibacterial and in vitro cytotoxic applications.

Green synthetic route of silver nanoparticles (AgNPs) has already been proved to be an advantageous over other physico-chemical approaches due to its simplicity, cost effectiveness, ecofriendly and nontoxicity. In this finding, aqueous Wedelia chinensis leaf extract (WLE) mediated synthesis of AgNPs was approached. Surface plasmon resonance (SPR) band at 408 nm preliminary indicated the formation of AgNPs, while TEM and XRD characterization confirmed the formation of spherically shaped and crystalline AgNPs with an average size of 31.

An approach to low-density polyethylene biodegradation by Bacillus amyloliquefaciens.

Low-density polyethylene (LDPE) is a major cause of persistent and long-term environmental pollution. In this paper, two bacterial isolates Bacillus amyloliquefaciens (BSM-1) and Bacillus amyloliquefaciens (BSM-2) were isolated from municipal solid soil and used for polymer degradation studies. The microbial degradation LDPE was analyzed by dry weight reduction of LDPE film, change in pH of culture media, CO estimation, scanning electron microscopy (SEM), and fourier transform infrared FTIR spectroscopy of the film surface.