Publications by authors named "Merin Reji"
Article Synopsis
- - Hyper Immunoglobulin D Syndrome (HIDS) is a rare genetic disorder that usually manifests in infants due to a mutation in the gene that produces mevalonate kinase (MVK), leading to recurrent fevers and gastrointestinal issues.
- - Patients typically experience high fevers every few weeks to months, alongside other symptoms such as joint pain, diarrhea, oral sores, and swollen lymph nodes.
- - The report highlights a unique case of HIDS diagnosed in an adult, emphasizing the difficulties in identifying this condition in adults due to its nonspecific symptoms and common childhood diagnosis.
The management of atopic diseases has been revolutionised by precision therapies and biological drugs that target specific immune proteins. This report elucidates a unique complication from the use of the monoclonal antibody, dupilumab, that primary care providers and subspecialists need to be aware of. A patient in her 40s consulted us for severe atopic asthma, food allergy and eczema involving the face and body.
View Article and Find Full Text PDFIbrutinib is Burton's tyrosine kinase inhibitor used in the treatment of chronic lymphocytic leukemia and other conditions. This drug has been generally thought to be well tolerated, although studies have identified a few distinct adverse effects, including gastrointestinal discomfort, nausea, diarrhea, and atrial fibrillation. Regarding cutaneous findings, ibrutinib has only been linked to two self-limiting forms of mild rashes generally.
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