Impact of Rutin and Vitamin C combination on oxidative stress and glycemic control in patients with type 2 diabetes.

Aim: This study aimed to investigate the effect of Vitamin C alone and in combination with Rutin on the glycemic control, insulin resistance, lipid profile and oxidative stress markers in patients with type 2 diabetes.

Methods: A prospective, randomized, controlled study conducted on 53 type 2 diabetes patients randomized into 3 groups; (group A) 20 received Rutin with vitamin C, (group B) 20receivedvitamin C and (group C)13 received antidiabetic treatment only. Fasting Blood Glucose (FBG), Hemoglobin A1c (HbA1c), fasting insulin, Malondialdehyde, Superoxide dismutase, Lipid profile and patients' quality of life (QOL) using SF-36 questionnaire were assessed in all patients at baseline and after 8 weeks.

Relation between plasma Apelin level and peripheral neuropathy in Type 2 diabetic patients.

Background: Peripheral neuropathy is one of the most common complications of both type 1 and type 2 diabetes, Long standing peripheral neuropathic pain associated with peripheral neuropathy occurs in one of six diabetic subjects, Apelin is a peptide secreted from adipocytes that seems to be beneficial in early detection of diabetic neuropathy, Itisnotedthatitincreasesindiabeticpatients and more in those with neuropathy.

Aim: We aimed to study the relation between plasma apelin levels and peripheral neuropathy in a sample of type 2 egyptian diabetic patients METHODS: The current study included 60 subjects with type 2 diabetes divided into 30 with diabetic neuropathy (group I) and 30 without diabetic neuropathy (group II) and 20 healthy subjects as a control group (group III). Fasting plasma glucose, Fasting insulin, HOMA- IR, Hemoglobin A1c, Total cholesterol, Triglycerides, High density lipoproteins, Low density lipoprotiens and Apelin levels were assessed.

Study of Irisin Hormone Level in Type 2 Diabetic Patients and Patients with Diabetic Nephropathy.

Background: Type 2 diabetic patients with diabetic nephropathy are associated with multifactorial abnormal energy metabolism. Irisin has been recently introduced as a hormone that is exercise-induced and is secreted by skeletal muscles. It is hypothesized that patients with chronic kidney disease usually have abnormal irisin levels.

Anti-islet Cell Antibodies in a Sample of Egyptian Females with Gestational Diabetes and its Relation to Development of Type 1 Diabetes Mellitus.

Background: Gestational diabetes mellitus is any degree of glucose intolerance with first diagnosis during pregnancy; it affects 3-10% of pregnancies. The presence of diabetes-related autoantibodies has shown to be able to predict the development of type 1 diabetes before hyperglycemia arises.

Objective: To recognize the prevalence of islet cell antibodies among a sample of Egyptian females with gestational diabetes and its possible relation to development of Type 1 diabetes within one year postpartum.