Publications by authors named "Meredith W Tan"

Article Synopsis
  • Advanced care planning (ACP) involves ongoing discussions among patients, families, and healthcare professionals about future healthcare needs.
  • Patients with rheumatic diseases often face significant symptoms and complications, but the rate of completed ACP in this group is low.
  • A quality improvement project in Singapore successfully increased ACP completion rates from 0 to 1 per month over a year through two Plan-Do-Study-Act cycles, indicating a need for further research on enhancing ACP engagement in these patients.
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Dengue virus (DENV), a Flavivirus, causes a broad spectrum of disease in humans with key clinical signs including thrombocytopenia, vascular leakage and hemorrhaging. A major obstacle to understanding DENV immunity has been the lack of a validated immune-competent mouse model. Here, we report the infection profiles of human clinical isolates of DENV serotypes 1-4 in an immune-competent mouse model.

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