Publications by authors named "Meredith Kinoshita"

Accuracy in the assessment of feed intake is important for preterm infants at risk of growth failure. Clinical observation tools are unvalidated in this population, and test weight measurement may be inaccurate in preterm infants taking small feed volumes. Test weights were performed to assess agreement between weights using a standardized protocol and a feed of known weight in preterm infants (born at <35 weeks gestational age [GA]) during their transition to oral feeding.

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Breastmilk confers empirical benefits for preterm infants, however direct breastfeeding rates in this population remain low. For preterm infants, it may be useful to assess the volume of breastmilk transferred from mother to baby when breastfeeding, particularly during transition to oral feeding when breastfeeding attrition is high. Establishing breastfeeding in preterm infants is complex and without knowledge of milk intake during breastfeeds there is risk of inaccurate feed supplementation with subsequent effects on growth and nutrition.

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Article Synopsis
  • Factor H autoantibodies can lead to atypical hemolytic uremic syndrome in children, and while 175 cases were examined, there is no established treatment protocol yet.
  • Out of 17 children with high levels of factor H autoantibodies, only six treated with eculizumab showed recovery, while traditional plasma exchange was less effective.
  • Due to high relapse rates without immunosuppression, the study suggests starting eculizumab therapy as the preferred treatment approach, despite the small sample size limiting the robustness of the findings.
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Aim: Perfusion Index (PI) is a quantifiable measurement of peripheral perfusion and may be a useful adjunct to the assessment of circulatory status in the newborn. (i) To assess reproducibility of PI and (ii) To determine whether there is a difference between simultaneously obtained limb measurements of PI in newborns <32 weeks GA in the transitional period.

Methods: Perfusion Index was measured in newborns <32 weeks during the first 48 h of life.

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