Publications by authors named "Meredith Cowden"
Graft-versus-host disease (GVHD) is a complication of hematopoietic cell transplantation (HCT) that has a low chance of complete remission and a substantial effect on morbidity and mortality. To better understand how to improve the field of GVHD research, management, and care, the cGVHD Eurograft Initiative organised a European community advisory board of patient advocates, with the assistance of the Lymphoma Coalition, to identify unmet needs. We present the results of this project in this Viewpoint, which identify unmet GVHD needs from the patient advocates' perspectives and provide five key actionable themes to improve GVHD management and care.
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- * The complexity of GVHD's biology and the lack of effective prognostic tools limit advancements in prevention and treatment for its severe forms, which are often difficult to study due to small patient populations.
- * Recommendations for research include better clinical and biological characterization of GVHD, conducting multisite studies, developing new targeted treatments for fibrotic changes, and setting clear endpoints for clinical trials to assess effectiveness.