Publications by authors named "Merdin L Ahmedov"
Background And Objective: Idiopathic intracranial hypertension (IIH) is a syndrome characterized with increased intracranial pressure and normal cerebrospinal fluid (CSF) composition. Treatment is mainly conservative, whereas CSF diversion surgery is the most frequently used surgical intervention. Endoscopic endonasal optic nerve decompression (EOND) is a newer surgical treatment of this patient group.
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- The study focuses on plurihormonal pituitary adenomas (PPAs) classified into two subtypes: PIT-1+ PPAs and PAwUIC, aiming to analyze clinicopathologic characteristics and surgical results.
- Out of 27 patients, 18 had PAwUIC and 9 had PIT-1+ PPAs, with a significant majority presenting as macroadenomas and showing aggressive features, including cavernous sinus invasion in 44.4%.
- Surgical outcomes revealed 57.1% gross total resection for PAwUIC and 77.8% for PIT-1+ PPAs, while hormone-secreting adenomas had a 100% remission rate, highlighting the
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- Temporal lobe epilepsy is the most common type of focal epilepsy, and surgical treatment, specifically anterior temporal lobe resection, is both effective and generally safe, though complications can occur.
- In a study of 53 patients, the overall complication rate was 19%, with surgical complications at 13.2% and neurological complications at 5.8%; notably, there were no persistent complications or deaths reported.
- While anterior temporal lobe resection is a reliable option, neurosurgeons must communicate potential risks effectively to candidates, emphasizing the importance of personal skill over reliance on modern technology.
Background: Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy. Focal cortical dysplasia is the most common dual pathology found in association with the hippocampal sclerosis. In this study, the effect of dual pathology on freedom from seizure was sought in patients with TLE.
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- The study examined levels of soluble human epoxide hydrolase-2 in patients with temporal lobe epilepsy, finding significantly higher levels in the temporal cortex compared to a control group.
- Correlation analysis revealed that higher enzyme levels in the temporal cortex were associated with increased levels in the hippocampal complex and a positive relationship with seizure frequency.
- The findings suggest that this enzyme could be a target for further research, as inhibiting it has shown promise in reducing seizures and neuroinflammation in previous studies.
Aim: To present the results of endoscopic endonasal repair of ventral midline skull base cerebrospinal fluid (CSF) leak (VMSBL) at our institution and to discuss the technique and results from a neurosurgical perspective.
Material And Methods: A retrospective analysis of all VMSBL cases that underwent endoscopic endonasal skull base approach (EESBA) for CSF leak repair at a single tertiary neurosurgical center was performed. Twenty six patients with an average age of 44.