A novel liposomal formulation for ocular delivery of caspofungin: an experimental study by quality by design-based approach.

This study focuses on the development of a Caspofungin liposome for efficient ocular delivery by enhancing corneal penetration. Quality by design (QbD) approach was adopted to identify critical factors that influence final liposomal formulation. The liposome developed using thin film hydration after optimization was subjected to characterization for physicochemical properties, irritation potential and corneal uptake.