Publications by authors named "Mercury Y Lin"
Article Synopsis
- * The Banff Working Group introduced a new classification for PyVAN based on viral load and interstitial fibrosis levels to better understand and categorize the condition.
- * In a study of 124 kidney transplant patients, the new classification did not effectively predict risk for graft failure, with class 3 showing the worst outcomes but no significant differences between classes 1 and 2; additional factors like post-transplant timing and inflammation also played a role in graft failure.
Background: For the better part of the past 6 decades, transmission electron microscopy (EM), together with routine light microscopy and immunofluorescence and/or immunohistochemistry (IHC), has been an essential component of the diagnostic workup of medical renal biopsies, particularly native renal biopsies, with increasing frequency in renal allograft biopsies as well. Studies performed prior to the year 2000 have indeed shown that a substantial fraction of renal biopsies cannot be accurately diagnosed without EM. Still, EM remains costly and labor-intensive, and with increasing pressure to reduce healthcare costs, some centers are de-emphasizing diagnostic EM.
View Article and Find Full Text PDFBackground: Nephropathy in patients with thymic diseases such as thymoma and myasthenia gravis (MG) is rare and has been described mostly as isolated case reports. Here we evaluate a series of kidney biopsies from patients with thymoma and/or MG from a single institution in order to better define the spectrum and relative frequencies of thymic disease-associated nephropathies.
Methods: We conducted a retrospective case series study of 32 462 native kidney biopsies from January 2005 through December 2019 at Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Interstitial eosinophilic aggregates in diabetic nephropathy: allergy or not?
Nephrol Dial Transplant
August 2015
Article Synopsis
- Interstitial eosinophilic aggregates (IEA) are often seen in renal biopsies, particularly in diabetic nephropathy (DN), and are defined as having 5 or more eosinophils per high power field.
- In a study at the University of Washington Medical Center, IEA were significantly more common in DN cases (41%) compared to other types of kidney diseases like IgA nephropathy and membranous nephropathy.
- The analysis indicated that greater interstitial fibrosis and tubular atrophy (IFTA) severity was linked to IEA presence in DN, but there was no correlation with drug allergies or types of medications taken by patients.
Article Synopsis
- Chondromatous hamartomas are the most frequent type of benign lung tumors and the third most common type of pulmonary nodules.
- These tumors typically have a structure made up of hyaline cartilage, fibromyxoid stroma, adipose tissue, and epithelial cells.
- A case is presented involving a healthy 60-year-old woman who had a predominantly cartilaginous hamartoma, which is a rare occurrence that happens in only 1% of hamartomas, and was successfully removed through thoracoscopic surgery.