Bemiparin in neonatal thrombosis: therapeutic dosing and safety.

Objective: To evaluate the therapeutic dose and safety of bemiparin in neonatal thrombosis treatment.

Study Design: A retrospective review was conducted on infants treated with bemiparin between 2018 and 2023 at a tertiary hospital.

Results: 72 neonates with a mean gestational age of 37 weeks were included.

Usefulness of daptomycin lock therapy in children with catheter-related bacteremia after failed vancomycin lock therapy.

Purpose: Catheter-related bacteremia (CRB) is a significant cause of morbidity, resource expenditure and prolonged hospital stays in patients with long-term catheters, whose numbers have increased considerably in recent years. Antibiotic lock therapy reaches high concentrations in the catheter, allowing good penetration into the biofilm, being vancomycin the most commonly used one in gram-positive infections. Several authors have recently reported the superior in vitro efficacy of daptomycin compared with vancomycin, especially for eradicating biofilms.