Liquid biopsy for and mutation testing in advanced colorectal cancer patients: the Argentinean experience.

To analyze the frequency of and hotspot mutations in circulating tumor DNA (ctDNA) from patients with metastatic colorectal cancer (mCRC). Observational, descriptive and retrospective study in mCRC patients with available ctDNA-based genotype of , and . The frequencies of plasma mutations for , and were 34% (± 7), 4% (± 3) and 4% (± 3), respectively.