Effect on the adherence to concomitant medications after initiation of treatment with direct-acting antiviral agents against hepatitis C virus.

Introduction: Many patients with hepatitis C virus (HCV) have associated comorbidities that require complex treatments. We sought to determine the impact of treatment with direct-acting antiviral agents (DAAs) for HCV on adherence to prescribed concomitant medications for associated comorbidities and to identify predictors of non-adherence to comedications.

Patients And Methods: HCV-infected patients treated with DAAs in a Spanish hospital between January 2015 and December 2016 and followed-up by the pharmacy unit were included in the study.

Concordance between pharmacotherapeutic complexity calculated and perceived by HIV+ patients with antiretroviral treatment.

Objective: To determine the difference between the pharmacotherapeutic complexity index by Medication Regimen Complexity Index  and it's perceived by patients through a visual analogue scale in patients  HIV+ with antiretroviral treatment.

Method: Prospective, observational study of patients HIV+ > 18 years of age  with stable antiretroviral treatment in the last three months, followed up by  external consultations of pharmaceutical care between October´17 and February ´18. The main variable of the study was the concordance between the median of  the score obtained in the pharmacotherapeutic complexity perceived  by the patients using the visual analog scale whose range of values oscillates between 0-10, categorized in low complexity (0-1) and high  complexity (2-10), and the median of the score obtained for the theoretical  pharmacotherapeutic complexity using the Medication Regimen Complexity  Index tool whose ranges of values oscillate between 1 and infinity, categorized  in low complexity (0-11) and high complexity > 11.

Evaluation of HIV+ patients experience with pharmaceutical care based on AMO-methodology.

Objective: To evaluate the experience of HIV+ patients with pharmaceutical care based on the ability-motivation-opportunity methodology. Method: Cross-sectional, unicentric study. The participants included were HIV+  patients attended during November-2016 and to whom the IEXPAC  questionnaire was conducted.

Identification of the Medication Regimen Complexity Index as an Associated Factor of Nonadherence to Antiretroviral Treatment in HIV Positive Patients.

Background: Multiple studies have identified a relationship between the complexity of a medication regimen and non-adherence. However, most studies in people who live with HIV (PLWH) have focused on antiretroviral use and have failed to consider the impact of other medications.

Objective: The aim of our study is to identify the Medication Regimen Complexity Index (MRCI) as an associated factor for nonadherence to antiretroviral treatment (ART).

Adequancy of treatment with canaglifozin alter alerts pharmacovigilance in the health management area.

Objective: To analyze the impact of a strategy on the suitability of canaglizozin, and its level of acceptance, after issuing recommendations based on drug surveillance alerts issued by the Spanish Medicines and Medical Devices Agency (AEMPS).

Design: A prospective intervention from may 2016 to october 2016. Location: South Seville Health Management Area.

Suitability of teriparatide and level of acceptance of pharmacotherapeutic recommendations in a healthcare management area.

Objective: To analyse the suitability of teriparatide prescriptions for osteoporosis treatment in a health management area, as well as the level of acceptance of pharmacotherapeutic recommendations made to physicians.

Design: A prospective interventional study conducted from february 2015 to june 2015.

Setting: South Seville Health Management Area.