Publications by authors named "Merce Aren"
Flow cytometry to detect bone marrow involvement by follicular lymphoma.
Cytometry B Clin Cytom
November 2022
Article Synopsis
- High-quality data on bone marrow involvement (BMI) in follicular lymphoma (FL) is scarce, which prompted researchers to develop a new flow cytometry protocol using a 10-color tube to evaluate BMI.
- Out of 52 patients studied, 67% showed BMI through flow cytometry, with a median involvement of 1.2% leukocytes, though some discrepancies were noted when compared to the gold standard of histopathology and IGH gene rearrangement.
- The study found significant heterogeneity in immunophenotypes of FL, indicating variation among patients, but overall, the new protocol effectively detected most cases of BMI in FL.