Insights into the impact of 6PPD-Q and 6PPD on nitrogen metabolism and microbial community in the anammox system.

N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) is an antioxidant commonly used in tire manufacturing, and its release into the environment has significantly increased due to rapid urbanization. When subjected to ozonation, 6PPD converts into the harmful pollutant 6PPD quinone (6PPDQ). These substances enter wastewater treatment plants (WWTPs) via stormwater runoff and pipelines, posing significant risks to the functional microorganisms.

Modulation of hemispheric asymmetry in executive control of attention in schizophrenia with atypical antipsychotic treatment: Potential benefits of olanzapine.

Deficits in executive control of attention have been reported in schizophrenia patients, but can be ameliorated by treatment of atypical antipsychotics along with the symptoms. However, it remains unclear whether this effect is related to a modulation of hemispheric asymmetry in executive control by the medicine. In this behavioral study, we employed a lateralized version of the attention network test to examine the hemispheric asymmetry of executive control in schizophrenia patients before and after olanzapine treatment, compared to matched healthy controls.

Spatiotemporal analysis and prediction of water quality in Pearl River, China, using multivariate statistical techniques and data-driven model.

Identifying spatiotemporal variation patterns and predicting future water quality are critical for rational and effective surface water management. In this study, an exploratory analysis and forecast workflow for water quality in Pearl River, Guangzhou, China, was established based on the 4-h interval dataset selected from 10 stations for water quality monitoring from 2019 to 2021. The multiple statistical techniques, such as cluster analysis (CA), principal component analysis (PCA), correlation analysis (CoA), and redundancy analysis (RDA), as well as data-driven model (i.

Exosomal miR-196a-5p enhances radioresistance in lung cancer cells by downregulating NFKBIA.

Radiation therapy is recognized as an effective modality in the treatment of lung cancer, but radioresistance resulting from prolonged treatment reduces the chances of recovery. MicroRNAs (miRNAs) play a pivotal role in radiotherapy immunity. In this study, we aimed to investigate the mechanism by which miR-196a-5p affects radioresistance in lung cancer.

Axial Attention Convolutional Neural Network for Brain Tumor Segmentation with Multi-Modality MRI Scans.

Accurately identifying tumors from MRI scans is of the utmost importance for clinical diagnostics and when making plans regarding brain tumor treatment. However, manual segmentation is a challenging and time-consuming process in practice and exhibits a high degree of variability between doctors. Therefore, an axial attention brain tumor segmentation network was established in this paper, automatically segmenting tumor subregions from multi-modality MRIs.

Insights into the fate of antibiotics in constructed wetland systems: Removal performance and mechanisms.

Antibiotics have been recognized as emerging contaminants that are widely distributed and accumulated in aquatic environment, posing a risk to ecosystem at trace level. Constructed wetlands (CWs) have been regarded as a sustainable and cost-effective alternative for efficient elimination of antibiotics. This review summarizes the removal of 5 categories of widely used antibiotics in CWs, and discusses the roles of the key components in CW system, i.

Platelets for cancer treatment and drug delivery.

Extensive research is currently being conducted into a variety of bio-inspired biomimetic nanoparticles (NPs) with new cell simulation functions across the fields of materials science, chemistry, biology, physics, and engineering. Cells such as erythrocytes, platelets, and stem cells have been engineered as new drug carriers. The platelet-derived drug delivery system, which is a new targeted drug delivery system (TDDS), can effectively navigate the blood circulatory system and interact with the complex tumor microenvironment; it appears to outperform traditional anticancer drugs; hence, it has attracted considerable research interest.

Genome-wide identification and expression analysis of calmodulin and calmodulin-like genes in wheat ( L.).

Calmodulin () and calmodulin-like () genes are widely involved in plant growth and development and mediating plant stress tolerance. However, the whole genome scale studies about and gene families have not been done in wheat, and the possible functions of most wheat gene members are still unknown. In this study, a total of 18 and 230 gene members were identified in wheat genome.

Genome-wide identification and expression analysis of the calmodulin-binding transcription activator (CAMTA) gene family in wheat (Triticum aestivum L.).

Background: Plant calmodulin-binding transcription activator (CAMTA) proteins play important roles in hormone signal transduction, developmental regulation, and environmental stress tolerance. However, in wheat, the CAMTA gene family has not been systematically characterized.

Results: In this work, 15 wheat CAMTA genes were identified using a genome-wide search method.

Transcriptome analysis of activated charcoal-induced growth promotion of wheat seedlings in tissue culture.

Background: Activated charcoal (AC) is highly adsorbent and is often used to promote seedling growth in plant tissue culture; however, the underlying molecular mechanism remains unclear. In this study, root and leaf tissues of 10-day-old seedlings grown via immature embryo culture in the presence or absence of AC in the culture medium were subjected to global transcriptome analysis by RNA sequencing to provide insights into the effects of AC on seedling growth.

Results: In total, we identified 18,555 differentially expressed genes (DEGs).

Fluorescent assay based on phenyl-modified g-CN nanosheets for determination of thiram.

Phenyl-modified graphitic carbon nitride nanosheets (Ph-g-CN NSs) were synthesized by a thermal copolymerization and ultrasonic exfoliation method. The Ph-g-CN NSs are used as a fluorescent assay for determination of thiram. The results of X-ray photoelectron spectroscopy, C solid-state nuclear magnetic resonance and Fourier transform infrared spectra confirm that phenyl group is integrated into the heptazine network of g-CN.

Relationship between land-use and sources and fate of nitrate in groundwater in a typical recharge area of the North China Plain.

Identification of different nitrate sources in groundwater is challenging in areas with diverse land use and multiple potential inputs. An area with mixed land-uses, typical of the piedmont-plain recharge area of the North China Plain, was selected to investigate different nitrate sources and the impact of land use on nitrate distribution in groundwater. Multiple environmental tracers were examined, including major ions, stable isotopes of water (δH-HO, δO-HO) and nitrate (δN-NO and δO-NO).

[A simple error-prone PCR method through dATP reduction].

Unlabelled: The error-prone PCR is one of the main methods for in vitro gene mutagenesis, usually through adding Mn2+ increasing Mg2+ and dCTP/dTTP concentration.

Objective And Methods: In this study, both the antifungal protein gene Ace-AMP1 from Allium cepa and the Bt toxin gene cry1A(c) from Bacillus thuringiensis were subjected to PCR mutagenesis through reducing the dATP concentration, but without adding Mn2+ or adjusting other PCR components.

Results: The result showed that the rates of base mutation and sequence variation were increased along with the decrease of dATP concentrations.