Experimental and computational techniques to investigate the protein resistance of zwitterionic polymers.

Most surfaces undergo non-specific protein adsorption upon direct contact with protein-containing environments, resulting in the formation of a protein corona, and the nature and composition of the corona affect the properties of the material. Zwitterionic polymers have oppositely charged groups in their repeating units, which facilitate the formation of a hydration layer on the surface through electrostatic interactions. The hydration layer possesses a strong water-binding ability and can prevent protein adsorption.

A Prediction Model for Assessing the Efficacy of Thermal Ablation in Treating Benign Thyroid Nodules ≥ 2 cm: A Multi-Center Retrospective Study.

Objectives: To develop and validate a prediction model utilizing clinical and ultrasound (US) data for preoperative assessment of efficacy following US-guided thermal ablation (TA) in patients with benign thyroid nodules (BTNs) ≥ 2 cm.

Materials And Methods: We retrospectively assessed 962 patients with 1011 BTNs who underwent TA at four tertiary centers between May 2018 and July 2022. Ablation efficacy was categorized into therapeutic success (volume reduction rate [VRR] > 50%) and non-therapeutic success (VRR ≤ 50%).

Is aromatic plants environmental health engineering (APEHE) a leverage point of the earth system?

It is important to note that every ecological niche in an ecosystem is significant. This study aims to assess the importance of medicinal and aromatic plants (MAPs) in the ecosystem from multiple perspectives. A primary model of Aromatic Plants Environmental Health Engineering (APEHE) has been designed and constructed.

Causal relationship between circulating cytokines and follicular lymphoma: a two-sample Mendelian randomization study.

Follicular lymphoma (FL), derived from germinal centre (GC) B cells, is a kind of systemic neoplasm. Even though FL is indolent, it remains an incurable haematology Neoplasm. Accumulating evidence has suggested that the circulating cytokine is associated with the development of FL, yet the causal relationship between FL and circulating cytokines remains undetermined.

Electrochemical Water Oxidation and CO Reduction with a Nickel Molecular Catalyst.

Mimicking the photosynthesis of green plants to combine water oxidation with CO reduction is of great significance for solving energy and environmental crises. In this context, a trinuclear nickel complex, [Ni(paoH)(PhPO)]·2ClO (), with a novel structure has been constructed with PhPO (phenylphosphonate) and paoH (2-pyridine formaldehyde oxime) ligands and possesses a reflection symmetry with a mirror plane revealed by single-crystal X-ray diffraction. Bulk electrocatalysis demonstrates that complex can homogeneously catalyze water oxidation and CO reduction simultaneously.

Two Novel Schiff Base Manganese Complexes as Bifunctional Electrocatalysts for CO Reduction and Water Oxidation.

One mononuclear Mn(III) complex [Mn(HO)(MeCN)](ClO) () and one hetero-binuclear complex [(CuMn(HO))(Cu)](ClO)·CHOH () have been synthesized with the Schiff base ligand (H = N,N'-bis(3-methoxysalicylidene)-1,2-phenylenediamine). Single crystal X-ray structural analysis manifests that the Mn(III) ion in has an octahedral coordination structure, whereas the Mn(II) ion in possesses a trigonal bipyramidal configuration and the Cu(II) ion in is four-coordinated with a square-planar geometry. Electrochimerical catalytic investigation demonstrates that the two complexes can electrochemically catalyze water oxidation and CO reduction simultaneously.

Analysis of clinical features of primary empty sella.

Objective: A retrospective analysis of clinical data of 60 patients with primary empty sella (PES) was conducted to further improve the understanding of the disease.

Methods: The clinical data of 60 patients diagnosed with PES admitted to the Department of Endocrinology of Wuhan Union Hospital for different reasons from January 2000 to September 2018 were analyzed.

Results: The 60 cases comprised 22 (36.

A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride.

A highly efficient synthesis reaction of carboxylic anhydrides catalyzed by triphenylphosphine oxide is described for the quick synthesis of a range of symmetric carboxylic anhydrides and cyclic anhydrides under mild and neutral conditions with a high yield. The system adopts the strong reactive intermediate PhPCl as the catalyst of carboxylic acid salt; driven by catalytic reaction, the synthesis takes a relatively short time to complete.

Reduced incidence of interstitial pneumonitis after allogeneic hematopoietic stem cell transplantation using a modified technique of total body irradiation.

Allogeneic hematopoietic stem cell transplantation is a curative-intent treatment for patients with high-risk hematologic diseases. However, interstitial pneumonitis (IP) and other toxicities remain major concerns after total body irradiation (TBI). We have proposed using linear accelerators with rice-bag compensators for intensity modulation (IM-TBI), as an alternative to the traditional cobalt-60 teletherapy with lung-shielding technique (Co-TBI).