Early evaluation of liver metastasis using spectral CT to predict outcome in patients with colorectal cancer treated with FOLFOXIRI and bevacizumab.

Purpose: Early evaluation of the efficacy of first-line chemotherapy combined with bevacizumab in patients with colorectal cancer liver metastasis (CRLM) remains challenging. This study used 2-month post-chemotherapy spectral computed tomography (CT) to predict the overall survival (OS) and response of CRLM patients with bevacizumab-containing therapy.

Method: This retrospective analysis was performed in 104 patients with pathologically confirmed CRLM between April 2017 and October 2021.

Development and Validation of a Clinical-Based Signature to Predict the 90-Day Functional Outcome for Spontaneous Intracerebral Hemorrhage.

We aimed to develop and validate an objective and easy-to-use model for identifying patients with spontaneous intracerebral hemorrhage (ICH) who have a poor 90-day prognosis. This three-center retrospective study included a large cohort of 1,122 patients with ICH who presented within 6 h of symptom onset [training cohort, = 835; internal validation cohort, = 201; external validation cohort (center 2 and 3), = 86]. We collected the patients' baseline clinical, radiological, and laboratory data as well as the 90-day functional outcomes.

Ascending aorta thrombosis combined with pulmonary artery thrombosis: a case report.

Ascending aorta thrombosis is very rare, and the exact mechanism of thrombosis in the context of high-speed blood flow is not fully understood. Pulmonary artery thrombosis is also a potentially life-threatening disease. Here we are reporting a case of ascending aorta thrombosis combined with pulmonary artery thrombosis.