Publications by authors named "Mengying Hei"

Superficial anaplastic lymphoma kinase (ALK)-rearranged myxoid spindle cell neoplasms are a recently identified subtype of cutaneous soft tissue tumors, distinct for their co-expression of CD34 and S100 and characterized by ALK gene rearrangements. Although 72 cases have been reported primarily as isolated case reports, this tumor subtype has yet to be included in the WHO classification of soft tissue tumors, underscoring the need for further study. In this study, we diagnosed two additional cases, both arising in the dermis and subcutaneous tissue.

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Article Synopsis
  • - The study addresses the difficulty of evaluating microvascular invasion (MVI) in hepatocellular carcinoma (HCC) patients due to a lack of sufficient tissue samples, impacting over half of patients.
  • - Researchers developed a deep learning model (MVI-DL) that uses tumor tissues from histological whole slide images to assess MVI status, achieving high accuracy in two separate patient cohorts.
  • - Key histological features linked to MVI status were identified, and the model shows promise as a practical clinical tool for MVI evaluation even when only limited tissue samples are available.
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