HMGB1 mediates epithelial-mesenchymal transition and fibrosis in silicosis via RAGE/β-catenin signaling.

Epithelial-mesenchymal transition (EMT) is implicated in the pathogenesis of silicosis. High mobility group box 1 (HMGB1) has been found to induce EMT in fibrotic diseases. Previous studies have revealed a critical role of HMGB1 in silicosis, whereas the detail mechanisms still obscure.

Photochemical transformation of CN under UV irradiation: Implications for environmental fate and photocatalytic activity.

In this study, the photo-transformations of bulk CN (CN) and oxidized CN (OCN) under UV-irradiation were examined. Through NO release measurements, we found that the photo-transformation rate of OCN is higher than that of CN. Various characterization results revealed the structural and chemical properties changes of CN and OCN after photo-transformation.

Transformation of atenolol by a laccase-mediator system: Efficiencies, effect of water constituents, and transformation pathways.

In this study, we investigated the transformation of atenolol (ATL) by the naturally occurring laccase from Trametes versicolor in aqueous solution. Removal efficiency of ATL via laccase-catalyzed reaction in the presence of various laccase mediators was examined, and found that only the mediator 2, 2, 6, 6-tetramethyl-1-piperidinyloxy (TEMPO) was able to greatly promote ATL transformation. The influences of TEMPO concentration, laccase dosage, as well as solution pH and temperature on ATL transformation efficiency were tested.