Publications by authors named "Mengyang Zhang"

Soil salinization is a major factor threatening global food security. Soil improvement strategies are therefore of great importance in mitigating the adverse effect of salt stress. Our study aimed to evaluate the effect of biochar (BC) and nitric acid-modified biochar (HBC) (1%, 2%, and 3%; m/m) on the properties of salinized soils and the morphological and physiological characteristics of pakchoi.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigated how the COVID-19 pandemic affected the distribution of systemic anti-cancer therapy (SACT) in Ireland from January 2019 to April 2021, utilizing national pharmacy claims data.
  • - Results showed a significant drop in the dispensing of immunotherapy and targeted therapy post-March 2020, with averages dropping by about 3.3 and 4.1 agents per 100,000 population monthly, indicating healthcare disruptions due to the pandemic.
  • - While the trend for endocrine therapy also slowed significantly after March 2020, no major changes were observed for other types of SACT during the pandemic period.
View Article and Find Full Text PDF

Transcription factors refer to types of proteins that perform significant functions in the process of gene expression regulation. The ethylene insensitive 3/ethylene insensitive 3-like () family, functioning as significant transcription factors regulating ethylene, plays a critical role in the growth and development of plants and participates in the plant's response to diverse environmental stresses. is an excellent native tree with high economic and ecological value.

View Article and Find Full Text PDF

Symmetry breaking has emerged as a novel strategy to enhance energy conversion and storage performance, which refers to changes in the atomic configurations within a material reducing its internal symmetry. According to the location of the symmetry breaking, it can be classified into spontaneous symmetry breaking within the material, local symmetry breaking on the surface of the material, and symmetry breaking caused by external fields outside the material. However, there are currently few summaries in this field, so it is necessary to summarize how symmetry breaking improves energy conversion and storage performance.

View Article and Find Full Text PDF

Superwetting/repelling coatings have been utilized to address the issue of oil contamination on lampblack prefiltration metallic foam by both academia and industry. Nevertheless, the widely adopted superamphiphobic coatings are currently costly and suffer from poor wear resistance. In this study, we propose an oil-resistant underoil superhydrophilic (LSH) coating by a dip-coating method.

View Article and Find Full Text PDF

Lungs are exposed to external oxidants from the environment as in harmful particles and smog, causing oxidative stress in the lungs and consequently respiratory ailment. The NF-E2-related factor 2 (Nrf2) is the one with transcriptional regulatory function, while its related protein Kelch-like ECH-associated protein 1 (Keap1) inhibits Nrf2 activity. Together, they form the Keap1-Nrf2 pathway, which regulates the body's defense against oxidative stress.

View Article and Find Full Text PDF

Anion-exchange membrane water electrolysis (AEMWE) has attracted attention owing to its operation in alkaline environments, which offers the advantage of not requiring the use of precious metals. Additionally, AEMWE exhibits higher kinetics in the hydrogen evolution reaction, enabling higher hydrogen production efficiency. The anion-exchange membrane (AEM) fabrication, catalyst design, and membrane electrode assembly (MEA) are crucial for enhancing the total water electrolysis performance.

View Article and Find Full Text PDF

Background: The healthcare system in Ireland was profoundly affected by COVID-19. This study aimed to explore the impact of the pandemic on cancer surgery in Ireland, from 2019 to 2022 using three national health data sources.

Methods: A repeated cross-sectional study design was used and included: (i) cancer resections from the National Histopathology Quality Improvement (NHQI) Programmes; (ii) cancer surgery from the National Cancer Registry Ireland (NCRI), and (iii) cancer surgery from Hospital Inpatient Enquiry (HIPE) System.

View Article and Find Full Text PDF

plays a crucial role in regulating the reproductive system, but there are few reports on the effects of on ovarian in dairy cows. Previous studies have verified the presence of a 67-bp mutation in the promoter region of the gene. Hence, we employed ovarian tissues = 2111) and blood samples ( = 108) from Chinese Holstein cows as experimental samples to examine the association between promoter variants and ovarian traits.

View Article and Find Full Text PDF

Colorectal cancer (CRC) ranks as the third most prevalent cancer globally and stands as the second principal contributor to cancer-related fatalities. Recently, emerging research has emphasized the role of pan apoptosis (PANoptosis) in tumor development and anti-tumor therapy. In the course of this investigation, we meticulously identified and conducted a correlation analysis between differentially expressed genes associated with PANoptosis in CRC (CPAN_DEGs) and the proportion of immune cells.

View Article and Find Full Text PDF

Background: The coronavirus disease 2019 (COVID-19) pandemic impacted cancer services worldwide. We examined the effect of the first three pandemic waves on the number of electronic (e)-referrals to rapid access clinics (RACs) for breast, lung and prostate cancer in Ireland.

Methods: This study used a retrospective, repeated cross-sectional design.

View Article and Find Full Text PDF

Background And Aims: Metabolic dysfunction-associated steatohepatitis (MASH)-related fibrosis is reversible. However, the dynamic morphology change in fibrosis regression remains unclear. We aim to explore the morphological characteristics of fibrosis regression in advanced MASH patients.

View Article and Find Full Text PDF

A metal-organic frameworks (MOFs)-in-MOF nanovehicle (160 nm), which was constructed with newly prepared ultrasmall Cu(I)Cu(II)-BTC MOFs (UCMs, 2.95 nm) loaded with doxorubicin (DOX) and a nuclear localization signal (NLS) peptide as multicores (UCMDNs) and ZIF-8 as the shell MOF, was proposed to cross layers of biological barriers with adaptive size evolution capacity for achieving efficient nucleus-targeted drug delivery. It first enhanced tumor tissue penetration through its larger nanosize effect.

View Article and Find Full Text PDF

The growth of industry has resulted in increased global air pollution, necessitating the urgent development of highly sensitive gas detectors. In this work, the adsorption of the Janus ZrSSe monolayer for CO, CO, NH, NO, NO, and O was studied by first-principles calculations. First, the stability of the ZrSSe monolayer is confirmed through calculations of cohesive energy and AIMD simulations.

View Article and Find Full Text PDF

Background: The widespread use of quercetin is limited by its instability, low solubility and poor oral bioavailability. Encapsulation of quercetin using a nanoparticle delivery system is an effective way to overcome these drawbacks.

Results: The effect of the molecular weight (M) of chitosan (CS) (100, 200, 500 and 1000 kDa) on quercetin-loaded chitosan nanoparticles (QCNPs) was investigated.

View Article and Find Full Text PDF

Chronic hepatitis B remains the primary cause of liver-related events in China. The World Health Organization set a goal to eliminate viral hepatitis as a public health threat by 2030. However, achieving this goal appears challenging due to the current low rates of diagnosis and treatment.

View Article and Find Full Text PDF

A six-cyclic crown ether-type pillar[5]arene was synthesized, and the five ethylene oxide loops were located outside the cavity and not affected by temperature changes which was confirmed by variable-temperature NMR experiment in DMSO-d6 and CDCl and 2D H-H NOESY experiment in CDCl. The six-cyclic pillar[5]-crown also showed greater binding ability of host-guest with bis(pyridinium) derivatives than conventional alkoxy pillar[5]arenes that illustrated through H NMR titration spectroscopic experiment in acetone-d6/CDCl (1 : 1) and UV-vis titration experiments in CHCl at room temperature. The five benzocrown ethers at the periphery were able to bind metal cations by H NMR titration spectroscopic experiment in CDCl/methanol-d4(9 : 1).

View Article and Find Full Text PDF

In recent years, there has been significant attention towards the development of catalysts that exhibit superior performance and environmentally friendly attributes. This surge in interest is driven by the growing demands for energy utilization and storage as well as environmental preservation. Spin polarization plays a crucial role in catalyst design, comprehension of catalytic mechanisms, and reaction control, offering novel insights for the design of highly efficient catalysts.

View Article and Find Full Text PDF

The nickel-based alloy Inconel 600, strengthened by solution treatment, finds extensive application as a heat exchange pipe material in steam generators within nuclear power plants, owing to its exceptional resistance to high-temperature corrosion. However, fretting corrosion occurs at the contact points between the pipe and support frame due to gas-liquid flow, leading to wear damage. This study investigates the fretting wear behavior and damage mechanism of the nickel-based alloy Inconel 600 and 304 stainless steel friction pairs under point contact conditions in a water environment.

View Article and Find Full Text PDF
Article Synopsis
  • - This study explores how bladder outlet obstruction (BOO) leads to fibrosis and elevated pressure in the bladder, focusing on the role of a mechanosensitive channel called Piezo1.
  • - Researchers used immunofluorescence staining and cultured bladder fibroblasts under different pressure conditions to analyze Piezo1 activity and the effects of various agonists and inhibitors.
  • - The findings reveal that high hydrostatic pressure enhances Piezo1 expression, promotes fibroblast proliferation, and increases pro-fibrotic factors, indicating that Piezo1 activation may worsen bladder fibrosis.
View Article and Find Full Text PDF

Background: Data on protection afforded by updated coronavirus disease 2019 (COVID-19) vaccines (bivalent/XBB 1.5 monovalent) against the emergent JN.1 variant remain limited.

View Article and Find Full Text PDF

Layered double hydroxides (LDHs), especially those containing nickel (Ni), are increasingly recognized for their potential in photo(-/)electrocatalytic water oxidation due to the abundant availability of Ni, their corrosion resistance, and their minimal toxicity. This review provides a comprehensive examination of Ni-based LDHs in electrocatalytic (EC), photocatalytic (PC), and photoelectrocatalytic (PEC) water oxidation processes. The review delves into the operational principles, highlighting similarities and distinctions as well as the benefits and limitations associated with each method of water oxidation.

View Article and Find Full Text PDF