Development of a regional carbon assimilation system and its application for estimating fossil fuel carbon emissions in the Yangtze River Delta, China.

Urban areas are the largest contributors to global fossil fuel carbon emissions, and controlling urban carbon emissions is critical to addressing climate change and reducing greenhouse gas emissions. However, estimates of urban emissions remain large uncertainties, making it difficult to accurately understand changes in urban carbon emissions and to assess the effectiveness of emission controls. Atmospheric CO observations, through data assimilation, can objectively invert changes in urban carbon emissions.

Facile Formation of Multifunctional Biomimetic Hydrogel Fibers for Sensing Applications.

To face the challenges in preparing hydrogel fibers with complex structures and functions, this study utilized a microfluidic coaxial co-extrusion technique to successfully form functional hydrogel fibers through rapid ionic crosslinking. Functional hydrogel fibers with complex structures, including linear fibers, core-shell structure fibers, embedded helical channels, hollow tubes, and necklaces, were generated by adjusting the composition of internal and external phases. The characteristic parameters of the hydrogel fibers (inner and outer diameter, helix generation position, pitch, etc.

China's Fossil Fuel CO Emissions Estimated Using Surface Observations of Coemitted NO.

Accurate estimates of fossil fuel CO (FFCO) emissions are of great importance for climate prediction and mitigation regulations but remain a significant challenge for accounting methods relying on economic statistics and emission factors. In this study, we employed a regional data assimilation framework to assimilate NO observations, allowing us to combine observation-constrained NO emissions coemitted with FFCO and grid-specific CO-to-NO emission ratios to infer the daily FFCO emissions over China. The estimated national total for 2016 was 11.

Safflower polysaccharide ameliorates acute ulcerative colitis by regulating STAT3/NF-κB signaling pathways and repairing intestinal barrier function.

This study is to investigate the effect of SPS on the UC model. An animal model of UC induced by DSS was developed using C57BL/6 mice. The body weight was recorded every day, and the symptoms related to UC were detected.

Improved estimation of CO emissions from thermal power plants based on OCO-2 XCO retrieval using inline plume simulation.

CO emissions from power plants are the dominant source of global CO emissions, thus in the context of global warming, accurate estimation of CO emissions from power plants is essential for the effective control of carbon emissions. Based on the XCO retrievals from the Orbiting Carbon Observatory 2 (OCO-2) and the Gaussian Plume Model (GPM), a series of studies have been carried out to estimate CO emission from power plants. However, the GPM is an ideal model, and there are a number of assumptions that need to be made when using this model, resulting in large uncertainties in the inverted emissions.

Elimination of Acrolein by Disodium 5'-Guanylate or Disodium 5'-Inosinate at High Temperature and Its Application in Roasted Pork Patty.

Acrolein (ACR) is a highly active, simple unsaturated aldehyde found in various high-temperature processed foods. Its long-term accumulation in the human body increases the risk of chronic diseases. Animal and plant foodstuffs are rich in disodium 5'-guanylate (GMP) and disodium 5'-inosinate (IMP), which are authorized flavor enhancers.

Large-scale land-sea interactions extend ozone pollution duration in coastal cities along northern China.

Land-sea atmosphere interaction (LSAI) is one of the important processes affecting ozone (O) pollution in coastal areas. The effects of small-scale LSAIs like sea-land breezes have been widely studied. However, it is not fully clear how and to what extent the large-scale LSAIs affect O pollution.

Synephrine, as a scavenger and promoter, cooperates with hesperidin to reduce acrolein levels.

Acrolein (ACR) is a harmful and active aldehyde produced in processed food that endangers foods safety. We undertook this work to explore the ACR-trapping ability of hesperidin (HES) and synephrine (SYN) from the diet. After comparing their ACR-trapping abilities, the reaction pathways of HES and SNY were analyzed using LC-MS/MS, and two adducts (HES-ACR-1 and SNY-2ACR) were synthesized, and their structures were identified by NMR.

Effects of hesperidin combined with synephrine on the capture of acrolein in a mouse model, or in humans by citrus consumption.

Acrolein (ACR) is a highly reactive α,β-unsaturated aldehyde that plays a key role in the pathogenesis of human diseases, such as atherosclerosis and pulmonary, cardiovascular, and neurodegenerative disorders. We investigated the capture capacity of hesperidin (HES) and synephrine (SYN) on ACR by individual and combined means , (utilizing a mouse model), and a human study. After proving that HES and SYN could efficiently capture ACR by generating ACR adducts , we further detected the adducts of SYN-2ACR, HES-ACR-1, and hesperetin (HESP)-ACR in mouse urine by ultraperformance liquid chromatography-tandem mass spectrometry.

Identification of key genes in sepsis by WGCNA.

When the body damages its own tissues in response to an infection, sepsis develops. Medical treatments are limited. It's important to understand the molecular mechanism behind sepsis pathogenesis and identify potential molecular treatment targets.

Rapid decline of carbon monoxide emissions in the Fenwei Plain in China during the three-year Action Plan on defending the blue sky.

The Fenwei Plain is one of China's most polluted regions, with poor atmospheric dispersion conditions and an outdated energy structure. After implementing multiple policies in recent years, significant reductions in air pollutant concentrations were observed. In this study, based on the Lagrangian-Bayesian inversion framework FLEXINVERT, we constructed a variable resolution inversion system focusing on the Fenwei Plain and inferred the carbon monoxide (CO) emissions using in-situ atmospheric CO observations from April 2014 to March 2020.

Modeling the biogenic isoprene emission and its impact on ozone pollution in Zhejiang province, China.

Isoprene is the most abundantly emitted biogenic volatile organic compound (BVOC), which plays an essential role in producing tropospheric ozone (O). However, the simulations of isoprene emissions have not been sufficiently verified over Yangtze River Delta (YRD), and few studies have specifically addressed its impact on O formation. In this study, we simulated the isoprene emissions in Zhejiang Province (ZJ), a region with the largest BVOC emission in YRD, in August 2020 using the Model of Emissions of Gases and Aerosols from Nature (MEGAN) and the latest Moderate Resolution Imaging Spectroradiometer (MODIS) products, and investigated its contributions to O using the Weather Research and Forecasting (WRF)-Community Multiscale Air Quality (CMAQ) model.

The Nord Stream pipeline gas leaks released approximately 220,000 tonnes of methane into the atmosphere.

Sudden mega natural gas leaks of two Nord Stream pipelines in the Baltic Sea (Denmark) occurred from late September to early October 2022, releasing large amounts of methane into the atmosphere. We inferred the methane emissions of this event based on surface in situ observations using two inversion methods and two meteorological reanalysis datasets, supplemented with satellite-based observations. We conclude that approximately 220 ± 30 Gg of methane was released from September 26 to October 1, 2022.

Black Carbon Emission Reduction Due to COVID-19 Lockdown in China.

During the Lunar New Year Holiday of 2020, China implemented an unprecedented lockdown to fight the COVID-19 outbreak, which strongly affected the anthropogenic emissions. We utilized elemental carbon observations (equivalent to black carbon, BC) from 42 sites and performed inverse modeling to determine the impact of the lockdown on the weekly BC emissions and quantify the effect of the stagnant conditions on BC observations in densely populated eastern and northern China. BC emissions declined 70% (eastern China) and 48% (northern China) compared to the first half of January.

Novel inhibitor of OCT1 enhances the sensitivity of human esophageal squamous cell carcinoma cells to antitumor agents.

Esophageal squamous cell carcinoma (ESCC) is one of the most fatal malignancies of the digestive system, and shows an especially high incidence in some regions of China. Octamer transcription factors are a family of transcription factors whose DNA-binding domain is a POU domain. OCT transcription factors (OCT-TFs) mediate maintenance of the pluripotency of embryonic stem cells.

Smoking Is Positively Associated with Antithyroperoxidase Antibodies and Antithyroglobulin Antibodies in Populations with Mildly Deficient Iodine Intake.

To evaluate the relationship between smoking and both antithyroperoxidase antibody (TPOAb) and antithyroglobulin antibody (TgAb) positivity in subjects from Panshan, Zhangwu, and Huanghua with mildly deficient, more than adequate, and excessive iodine intake, respectively. Smoking-related data were collected by questionnaire, and laboratory measurements of TPOAb, TgAb, and thyrotropin (TSH) were determined at baseline and follow-up. (1) A 1.