Publications by authors named "Mengwei Chou"
Article Synopsis
- A new case of OS was identified due to an unprecedented mutation in the associated gene, presenting with significant skin issues and leading to cancer on the foot.
- This discovery highlights the broad range of symptoms related to the gene's mutations and emphasizes the importance of continuous monitoring for affected individuals.
Introduction: Extraocular sebaceous carcinoma (SC), particularly those outside the head and neck region, is rare and not well-described.
Purpose: This study aimed to explore the epidemiology and identify the prognostic factors of non-head and neck SC, describe the possible relevant factors of distant metastasis, and provide implications for distant metastasis screening.
Methods: Data from the 17 registries in the Surveillance, Epidemiology, and End Results database were retrospectively collected for patients with SC outside the head and neck from 2000 through 2020.
Article Synopsis
- Pachyonychia congenita (PC) is a rare genetic disorder marked by thickened nails and skin problems on the feet, caused by mutations in specific keratin genes.
- A study focused on a Chinese family with PC who had severe palmoplantar keratoderma and a new case of acral melanoma, involved genetic testing to find the underlying mutation.
- Researchers discovered a new mutation in the KRT16 gene (p.Arg127Pro) in the affected patient, which has previously been seen in Dutch patients with PC, but this is the first report in a Chinese individual.