Talarolactone A, an Isocoumarin Derivative Fused with Dihydrothiophene with Selective Antimigratory Activity from the Endolichenic Fungus sp.

A 3,4-dihydroisocoumarin derivative fused with dihydrothiophene, talarolactone A (), and two known compounds, terreusinone () and 4,6-dihydroxy-5-methylphthalide (), were isolated from sp. associated with . The structure of was deduced from extensive spectroscopic data, electronic circular dichroism calculations, and X-ray diffraction analyses.

Enhanced curcumin solubility and antibacterial activity by encapsulation in PLGA oily core nanocapsules.

Infections caused by bacteria represent an emerging public health threat due to the development of antibiotic resistance in bacteria. Curcumin (CUR), a naturally derived substance, is found to be effective against several bacteria. However, its use is limited by its low water solubility and rapid degradation profile.

A high throughput method for total alcohol determination in fermentation broths.

Background: The potassium dichromate oxidation method used in determination of alcohols in fermentation has two major disadvantages. This method cannot be used to determine alcohols in raw fermentation broth samples, which often contain various reducing sugars. The method is not environment friendly due to the carcinogenicity of Cr (VI) used.

Active Metabolites from Endolichenic Fungus Talaromyces sp.

The active metabolites investigation of Talaromyces sp. (strain No. MH551540) associated with Xanthoparmelia angustiphylla afforded one new δ-lactone, talaromycin A (1), together with six known compounds, clearanol A (2), 6-methylbiphenyl-3,3',4,5'-tetraol (3), desmethylaltenusin (4), ergone (5), ergosterol (6), and palmitic acid (7).