Publications by authors named "Mengtian Han"
A unified evaluation descriptor for π-bridges applied to metalloporphyrin derivatives.
Phys Chem Chem Phys
September 2024
Article Synopsis
- The study focuses on porphyrins with an A-π-D-π-A configuration, aiming to enhance their properties through variations in the π-bridge components (thiophene and selenophene) and connection types (single, ethylenic, or fused bonds).
- It highlights the importance of π-bridges in influencing molecular structure and performance, while revealing that their primary role is to enable strong interactions between donor and acceptor fragments, rather than merely showcasing their own characteristics.
- Results indicate that optimizing π-bridge properties can lead to improved electronic performance, such as higher open circuit voltages and stable film morphologies, suggesting a new descriptor for evaluating π-bridges in molecular design.
Ethnopharmacological Relevance: Jizhi syrup (JZTJ) is composed of eight medicinal herbs, including Houttuynia cordata, Fagopyrum dibotrys, Ilex chinensis, Ephedra sinica, Aster tataricus, Peucedanum praeruptorum, Citrus aurantium and Glycyrrhiza uralensis. It is mainly used for coughing caused by exogenous wind heat. Symptoms include fever, aversion to cold, chest and diaphragm tightness, cough and sore throat; and acute bronchitis and acute exacerbation of chronic bronchitis with the above symptoms.
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- China and India each have rich traditional medicine systems, with China identifying 12,694 medicinal materials and India 7,263, including various regional practices like traditional Chinese medicine and Ayurveda.
- The study aims to explore and compare the characteristics of these medicinal materials in terms of their properties, therapeutic uses, and exchange potential between the countries.
- Findings indicate significant overlap, with 1,048 common medicinal materials used in both countries, highlighting plants as the primary source and a focus on treating digestive diseases.
Background: Ershiwuwei Zhenzhu pills was originally recorded in the Tibetan medical book Si Bu Yi Dian in the 8th century AD and is now included in the Pharmacopoeia of the People's Republic of China (2020). The pills can calm the nerves and open the mind as well as treat cerebral ischemia reperfusion injury, stroke, hemiplegia. However, its quality standards have not yet been established, and the therapeutic effect on cerebral ischemia by regulating the mitochondrial apoptosis pathway has not been elucidated.
View Article and Find Full Text PDFThis review discusses the variety, chemical composition, pharmacological effects, toxicology, and clinical research of corals used in traditional medicine in the past two decades. At present, several types of medicinal coral resources are identified, which are used in 56 formulas such as traditional Chinese medicine, Tibetan medicine, Mongolian medicine, and Uyghur medicine. A total of 34 families and 99 genera of corals are involved in medical research, with the Alcyoniidae family and genus being the main research objects.
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- Erigeron breviscapus is a traditional medicine used by several ethnic minorities in China for treating ailments, including ischemic stroke, although its mechanisms are not fully understood.
- This study employs advanced metabonomics techniques to understand how Erigeron breviscapus injection impacts a rat model of ischemic stroke and its interactions with mitochondrial apoptosis pathways.
- Results indicate that the injection significantly reduces cerebral infarction size and improves tissue health, as evidenced by an increase in Nissl bodies in the treated rats.
NF-Y, a critical transcription factor, binds to the CCAAT-box in target gene promoters, playing a pivotal role in plant development and abiotic stress response. OsNF-YC5, encodes a putative subunit of the NF-Y transcription factor in rice, had an undetermined function. Our research revealed that OsNF-YC5 is induced by high salinity and exogenous abscisic acid (ABA).
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