Background: Metabolic syndrome (MetS) has been related to the increased incidence of esophageal cancer (EC). The aim of the study was to evaluate the influence of MetS on prognosis of patients with surgically treated EC in a systematic review and meta-analysis.
Methods: An extensive search was conducted on PubMed, Embase, Web of Science, Wanfang, and CNKI to identify relevant cohort studies.
Polo-like kinase 3 (Plk3) is involved in tumor development with a tumor suppressive function. However, the effect of Plk3 on the chemoresistance remains unclear. It has been documented that activation of the PI3K/AKT signaling pathway by PTEN loss significantly enhances chemoresistance in nonsmall-cell lung cancer (NSCLC).
View Article and Find Full Text PDFMetal-organic frameworks have been widely used as photocatalytic materials. In this paper, a novel photocatalyst HSO-MIL-53(Fe) with acidity regulating groups was successfully synthesized by the solvothermal method and applied to remove carbamazepine (CBZ) and ibuprofen (IBP). The photodegradation efficiency of vis/HO/HSO-MIL-53(Fe) can reach 100% when the pH value is 8 or 9.
View Article and Find Full Text PDFAlthough manganese(II) is known to have no role in peroxymonosulfate (PMS) activation, through a series of sulfamethoxazole (SMX) oxidation experiments, we found that the addition of pyridine organic ligands can improve the catalytic activity and accelerate SMX oxidation. For the organic ligands to be effective: the stability constant of the Mn(III) complex should be higher than that of the Mn(II) complex. A positive correlation was observed between the SMX oxidation rate and Mn(II) concentration, and the maximum PMS utilization efficiency was achieved.
View Article and Find Full Text PDFFish Shellfish Immunol
July 2018
Toll-like receptor (TLR) is considered to be an evolutionarily conserved transmembrane protein which promotes the Toll signal pathway to active the expression of transcription factors in the innate immunity of the organism. In this study, a full length of TLR homologue of 2525bp in Mytilus coruscus (named as McTLR-a, GenBank accession no: KY940571) was characterized. Its ORF was 1815 bp with a 5'untranslated region (UTR) of 128 bp and a 3'UTR of 582 bp, encoding 602 amino acid residues with a calculated molecular weight of 70.
View Article and Find Full Text PDFTitanium xerogel coagulant (TXC) worked better than titanium tetrachloride (TC) and polytitanium chloride (PTC) in a wider pH/dose range for the removal of turbidity. However, the underlying mechanisms were not comprehensively understood. In this work, the better coagulation performance of TXC than TC and PTC was systematically elucidated from the following aspects: the physicochemical properties of the three coagulants, the removal of turbidity and organic matter, and the complexation reactions in coagulation.
View Article and Find Full Text PDFHeat shock proteins (HSPs) play significant roles in the immune response of fish in defending against diverse environmental threats or stresses. In this study, two complete HSP70 and HSP90 genes of Larimichthys crocea (designated as LycHSP70 and LycHSP90) were identified and characterized (GenBank accession no. KT456551 and KT456552).
View Article and Find Full Text PDFMar Pollut Bull
October 2016
Heat shock protein 90 (HSP90) is a conserved molecular chaperone contributing to cell cycle control, organism development and the proper regulation of cytosolic proteins. The full-length HSP90 cDNA of Mytilus coruscus (McHSP90, KT946644) was 2420bp, including an ORF of 2169bp encoding a polypeptide of 722 amino acids with predicted pI/MW 4.89/83.
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